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Showing 1 to 1 of 1 for “"Nucleotide Discrimination"”.
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The effect of oxidized guanines on DNA synthesis by DNA polymerase β
… instruct the addition of correct corresponding nucleotides (also termed fidelity) to form a new DNA strand. DNA replication is extremely accurate to prevent deleterious alterations to the genetic code. However, DNA is damaged more than 10,000 times per cell per day. …