Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Nucleic acid testing"”.
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Development of Field-deployable Nucleic Acid Testing Platforms
… focused on the development of field-deployable nucleic acid testing platforms to allowed rapid detection and quantification of nucleic acids. Two distinct platforms suitable for nucleic acid testing in resource-limited settings were developed. First, a paper-based diagnostic device was …
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Smartphone-based systems for mobile infectious disease detection and epidemiology
… second one is for the multiplexed detection of nucleic acids of pathogens for equine respiratory infections. Both platforms utilize a smartphone camera as the sensor in conjunction with a handheld cradle that interfaces the phone with a microchip for the on-chip nucleic acid testing of …
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Designing Next Generation Nucleic Acid Diagnostics Using Synthetic Biology and Artificial Intelligence
Nucleic Acid Testing (NAT) is an indispensable tool for effective disease diagnosis. Analyzing pathogen and host RNA or DNA often provides otherwise unobtainable information necessary for proper patient treatment. Unfortunately, a number of technical barriers prevent the expansion of NAT technology …
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A Rapid and Power-Efficient Laser-Induced Graphene Micro-Thermocycler for DNA Polymerase Chain Reaction
… COVID-19 pandemic pushes for the need for rapid nucleic acid testing, and for early diagnosis compared to antigens testing. This research aims to develop a laser induced graphene (LIG) heater as the heating element for PCR point-of-care testing (POCT), as the PCR detection result is highly …
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Cell-free synthetic biology for affordable, on-demand diagnostics
Detection of biomarkers, such as nucleic acids, performs critical roles in managing infectious disease outbreaks, point-of-care testing, and public health monitoring. However, many diseases and public health problems suffer from a lack of affordable, portable tests that can be used to sensitively …
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Development of Universal Biosensing Platforms Based on CRISPR/Cas12a systems
… of CRISP/Cas12a based biosensing platforms for nucleic acid and protein detection. Two distinct CRISPR/Cas based diagnostic methods were developed. The first developed method is a plasmonic CRISPR Cas12a assay for colorimetric detection of viral nucleic acid. This assay generates colorimetric …