Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Nuclear position"”.
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Genetic analysis of the maintenance of neuronal morphology in Drosophila melanogaster
… is required post-mitotically to maintain proper nuclear positioning. Using a genetic screen, I identified loss-of-function alleles of kinesin heavy chain, encoding a subunit of the plus-end-directed microtubule motor Kinesin, as suppressors of the rough eye and nuclear mispositioning in Glued …
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Topology of Genes in Mammalian Cell Nuclei with Special Emphasis on the MLL Gene and Its Translocation Partners
… was developed to precisely determine gene positions in the 3D space of the spherical interphase nucleus of hematopoietic cells. The nuclear localization of a gene relative to the nuclear center and the nuclear periphery was determined. To provide a general understanding of the distribution …
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Interplay between interkinetic nuclear migration and cell fate determination in the developing zebrafish retina
… cells (RPCs), whose clonal sizes and compositions are stochastically determined. However, the biological processes that contribute to the stochastic cell fate decision making of RPCs remain largely unexplored. Another major hallmark of neural development is the oscillatory movement of …
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Genomic and microscopic dissection of nuclear compartmentalization and function
… for gene expression regulation. Abnormal nuclear organization is related to disease. Microscopy measurements of individual genes reveal a population-based, statistical gradient of increased gene activity from the nuclear periphery to the center. Sequencing-based methods (Hi-C, DamID) …