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Showing 1 to 3 of 3 for “"Nr2e1"”.

  1. Genetic and genomic studies of mouse and human NR2E1 in cortical disorders, aggressive behaviour, and psychiatric disease

    … The 'fierce' mouse has a spontaneous deletion of Nr2e1 that results in a complex phenotype that includes cortical hypoplasia and socially abnormal behaviours. Notably, functional protein and regulatory equivalency of mouse and human NR2E1 has been established. Furthermore, human studies implicate …

    ubc Repository record for Genetic and genomic studies of mouse and human NR2E1 in cortical disorders, aggressive behaviour, and psychiatric disease (opens in a new tab)

  2. Identifying regulators of neural stem cell fate and tumourigenesis

    … receptor subfamily 2, group E, member 1 or NR2E1) is expressed in NSCs both during development and in adults. TLX mutations are linked to microcephaly and hereditary cases of bipolar disorder, whereas high TLX expression is a diagnostic marker of aggressive glioblastoma tumours and is …

    cambridge Repository record for Identifying regulators of neural stem cell fate and tumourigenesis (opens in a new tab)