Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Novicida"”.
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Identification and Characterization of the Hfq protein and small RNAs in Francisella novicida
… in <italic>F. tularensis</italic> subsp. <italic>novicida</italic> strain U112. The Hfq protein is recognized as an important regulatory factor in a variety of cellular processes, including stress resistance and pathogenesis, and has been shown in several bacteria to interact with small RNAs as a …
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Roles of Cytosolic Nucleic Acid Sensors in Cancer and Infection
… <em>Francisella tularensis </em>subspecies <em>novicida </em>(<em>F. novicida</em>) and induces inflammasome responses. Type I interferon (IFN) signaling drives activation of AIM2 inflammasome in <em>F. novicida</em>-infected macrophages; however, the relative contribution of IFNs and …
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The Potential Role for CapB in Pathogenesis of Francisella tularensis
… animals. Francisella tularensis subspecies novicida has been used by many researchers in genetic pathogenesis experiments to try to elucidate genes responsible for virulence factors. One of these virulence factors was a capsular material which has been thought to be involved in either …
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Surface Polysaccharides of Francisella tularensis: Further Characterization, Role in Virulence, and Application to Novel Vaccine Strategies
… the efficacy of these mutant strains. F. novicida is a subspecies of F. tularensis and usually classified as being non-encapsulated. However, F. novicida has a similar capsule glycosylation locus as F. tularensis and could produce a similar capsule-like complex that has previously been …
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Glycan polymeric prodrugs against pulmonary intracellular alveolar infections
… improved protection against intracellular F. novicida infection in mice challenge models compared to free antibiotic. When intratracheally administered to the lungs of mice in a prophylactic setting, poly(Man-co-CTM) improved survival in 50% of the mice and in a post-infection treatment …