Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Novel Chemical Entities"”.
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Novel chemical entities against tropical diseases: Peptidomimetic lipopeptides as new anti-orthoflavivirals and 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives as new antimalarials
Contains fulltext : 310090.pdf (Publisher’s version ) (Open Access)
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Novel Diagnostics and Therapeutic Approaches for Supratentorial Ependymoma
… for C11orf95-RELA-fusion ependymoma as well novel therapeutic approaches to treat the disease. Antibodies raised against the C11orf95-RELA fusion epitope were selected through phage-display and tested in immunoblot and immunohistochemistry assays before lead immunoglobulins were subjected to …
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Computer modelling of metabolic adaptions during mitochondrial dysfunction and machine learning to predict novel mitochondrial disease genes
… and are primarily responsible for generating chemical energy in the form of adenosine triphosphate. This thesis investigates two main causes of mitochondrial dysfunction: mitochondrial toxicity arising from side-effects of drugs; and mitochondrial diseases arising from defects in …