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Showing 1 to 2 of 2 for “"Nova proteins"”.

  1. Interactions between Nova and brPTB Proteins in Alternative Splicing and Nuclear Localization

    <p>The Nova paraneoplastic antigens are neuron-specific RNA-binding proteins that are essential for neuronal viability and participate in the control of alternative splicing. In this study, the yeast two-hybrid system is used to isolate Nova-1nteracting proteins. A novel RNA-binding protein named …

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  2. Nova Regulation of Alternative Splicing in the CNS

    <p>Nova-1, an autoantigen in paraneoplastic opsoclonus myoclonus ataxia (POMA), a disorder associated with gynecologic cancer and CNS motor dysfunction, is a neuronspecific nuclear RNA binding protein. The work presented here confirms that Nova-1 acts as a regulator of alternative splicing in vivo. …

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