Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Notch signals"”.
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Interpreting Notch signals: characterisation of dynamic transcription hubs by live imaging
The Notch signalling pathway, crucial for development, activates upon cell-to-cell contact. Despite lacking any amplification, activation of target genes is achieved robustly and efficiently after contact-induced cleavage of the Notch transmembrane protein. How relatively few molecules of the …
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Notch activation and clone fate in intestinal homeostasis and inflammation
The Notch signalling pathway is a highly conserved pathway that has important and often differing roles and functions depending on the tissue. In the intestinal epithelium Notch signals are important for determining cell fate between the absorptive and secretory lineage and regulating the …
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Local and Systemic Consequences of Reducing Notch Signaling in Skin Keratinocytes
Notch is a transmembrane receptor that mediates short-range signaling between neighboring cells. Notch signaling has been implicated in various cellular and developmental processes essential in the life of metazoans. Specifically, Notch signaling plays a critical role in mammalian skin. Removal of …
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Jagged1 regulates adult neural stem cell maintenance and multipotency through activation of Notch1
… sind die bis jetzt am besten beschriebenen. Von Notch-Delta Signalmolekülen weiss man, dass sie in <br>Entwicklungsentscheidungen vieler Gewebe in Organismen von Drosophila bis hin zum Menschen involviert sind. Sowohl der Notch Rezeptor als auch dessen Liganden Delta und Jagged sind …