Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Nosocomial pathogens"”.
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Proteomics as a tool for the characterisation of nosocomial pathogens
… approaches for the characterisation of two major nosocomial pathogens, S. aureus and C. difficile and to further investigate the intraspecies diversity of C. difficile using a genotypic approach. The surface-associated proteins of S. aureus and intracellular stable ribosomal proteins of C. …
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Evolutionary Genomics of Cystic Fibrosis and Nosocomial Pathogens of the Mycobacterium abscessus species complex
… to examine the within host evolution of these pathogens to uncover how these environmental organisms were adapting to the CF lung. This thesis also used whole genome sequencing to explore the largest known outbreak of MABSC infections, a post-surgical wound infection epidemic in Brazil. Through …
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Investigation of the prevalence of opportunistic gram negative pathogens in the water supply of a haematology unit, and the application of point-of-use filtration as an intervention.
… examined whether water systems are reservoirs of nosocomial pathogens. This study investigated longitudinal recovery of the opportunistic pathogens Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Acinetobacter baumannii from water outlets of a haematology unit and evaluated Point-Of-Use …
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Regulation of blaFOX-5b Expression Within Two Different Genetic Backgrounds: Klebsiella pneumoniae and Escherichia coli
… pneumoniae and Escherichia coli are major nosocomial pathogens. A clinical isolate of K.pneumoniae and E. coli were found to produce a novel plasmid-encoded ampC P-lactamase gene, blaFOX-5b- These isolates conferred high level resistance to a broad spectrum of antibiotics, including third …
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Mobilome and antibiotic resistance in Acinetobacter baumannii
… and the dissemination of resistance genes among nosocomial pathogens around the world.
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Molecular Mechanisms of Antimicrobial Resistance In Multi-Drug Resistant Enterococci
… health threat. Enterococci are recalcitrant, nosocomial pathogens that can be intrinsically resistant to valuable antibiotics, like beta-lactams, or evolve resistance to all existing antimicrobials. The LiaFSR system regulates resistance to cell membrane (CM) stressors like daptomycin (DAP), a …
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Characterisation of novel and complex mechanisms of antobiotic resistance using a proteomics approach
… among multi drug resistant Gram-negative nosocomial pathogens. These organisms display non- susceptibility to the majority of routinely used antibiotics, causing infections which are more difficult to treat and increase the duration of patient recovery. Due to the plethora of resistance …
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Detection of Vancomycin resistant Enterococci from clinical specimens at University Teaching Hospitals
… tract of humans. They have emerged as important nosocomial pathogens due to their ability to acquire and confer antimicrobial resistance genes, hence making management of infections due to Enterococcus species difficult. Resistance to glycopeptide antibiotics, especially Vancomycin is of special …
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Detection of Vancomycin resistant Enterococci from clinical specimens at University Teaching Hospitals
… tract of humans. They have emerged as important nosocomial pathogens due to their ability to acquire and confer antimicrobial resistance genes, hence making management of infections due to Enterococcus species difficult. Resistance to glycopeptide antibiotics, especially Vancomycin is of special …
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Mechanism of Candida Albicans Biofilm and Virulence Inhibition By A Bacterial Secreted Factor
… most important and problematic, opportunistic nosocomial pathogens and are often co-isolated during infection. Surprisingly, these two species antagonize each other’s virulence in both nematode infection and in vitro biofilm growth.</p> <p>Herein we identify the <em>E. faecalis</em> secreted …
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The Influence of ampC Expression and Penicillin Binding Protein Binding on the Variation of ß-lactam Induction Potential in Three Genera of Enterobacteriaceae
… Enterobacteriaceae family and are significant nosocomial pathogens. These organisms encode inducible, chromosomal AmpC ß-lactamases which can cause, if overproduced, resistance to all ß-lactams except the fourth generation cephalosporins and the carbapenems. The interaction of ß-lactams with …