Global ETD Search
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Showing 1 to 2 of 2 for “"Normal Tissue Contamination"”.
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Accurate Identification of Significant Aberrations in Cancer Genome: Implementation and Applications
… scale with high resolution. However, due to normal tissue contamination, the observed intensity signals are actually the mixture of copy number signals contributed from both tumor and normal cells. This genetic confounding factor would significantly affect the subsequent copy number analyses. …
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Modeling and Characterization of Dynamic Changes in Biological Systems from Multi-platform Genomic Data
… detect genomic deletion type, estimate normal tissue contamination, and accordingly recover the true copy number profile in cancer cells.