Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"Nonlinear optical microscopy"”.
-
Ptychography for Nonlinear Optical Microscopy
In this thesis I will introduce a novel nonlinear optical microscopy method to address some of the shortcomings in the current nonlinear optical microscopy literature and offer a supplement to traditional fluorescent microscopy for label free optical biomedical imaging. In order to demonstrate this …
-
Nonlinear optical microscopy and spectroscopy by pulse shaping of a coherent fiber supercontinuum
Nonlinear optical microscopy and spectroscopy enable three-dimensional sub-µm-resolution imaging with deeper penetration and reduced photodamage, and have been established as powerful methods in biomedicine. The most appealing aspect of nonlinear optical imaging is the wealth of molecular contrast …
-
Polarization-dependent nonlinear optical microscopy methods for the analysis of crystals and biological tissues
… environments. Polarization-dependent SHG microscopy methods were developed to assess the presence of multidomain crystals to provide a handle on crystal quality. In addition, polarization-dependent two-photon excited fluorescence (TPEF) microscopy was developed as a complementary method to …
-
Computational methods for fast nonlinear optical microscopy of label-free metabolic dynamics in live organisms
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-08-01
-
Wide-field Polarimetric Second Harmonic Generation Microscopy for Histology Imaging
Nonlinear optical microscopy provides several contrast mechanisms including second harmonic generation (SHG), third harmonic generation (THG) and multiphoton excitation fluorescence (MPEF) that can contribute with additional information to hematoxylin and eosin (H&E) stained tissue histopathology, …
-
Developing Single-Laser Sources for Multimodal Coherent Anti-Stokes Raman Scattering Microscopy
Coherent anti-Stokes Raman scattering (CARS) microscopy has developed rapidly and is opening the door to new types of experiments. This work describes the development of new laser sources for CARS microscopy and their use for different applications. It is specifically focused on multimodal …
-
Identification of Image-based Markers for Oral Pre-cancers and Cancers using in-vivo Multimodal Imaging
… precancers and cancers for biopsy guidance. Nonlinear optical microscopy (NLOM) has shown potential to identify optical signatures associated with microstructural and biochemical alterations in cancer, providing in-vivo three-dimensional imaging with contrast from endogenous fluorophores, …
-
Ultrafast Probing of Nonlinear Dynamics in Quantum Materials: Beyond Linear Response Probes
… spectroscopy, second harmonic generation microscopy, and high field THz excitation spectroscopy, are capable of probing the properties of quantum materials that are not accessible with linear response techniques. By employing these techniques, this thesis visualizes different types of …
-
Multiphoton microscopy for stain-free slide-free histopathology
… highly time- and labor-intensive. Label-free nonlinear optical microscopy, which produces high-resolution images with rich functional and structural information based on intrinsic molecular contrast, has demonstrated significant potential to overcome these problems by leveraging its …
-
Development and applications of high speed and hyperspectral nonlinear microscopy
Nonlinear microscopy refers to a range of laser scanning microscopy techniques that are based on nonlinear optical processes such as two-photon excited fluorescence and second harmonic generation. Nonlinear microscopy techniques are powerful because they enable the visualization of highly …
-
Third Harmonic Generation: A Method for Visualizing Myelin in the Murine Cerebral Cortex
… myelin in gray matter. First, we engage in THG microscopy using an optical parametric oscillator pumped by a titanium-sapphire laser to demonstrate the utility of the technique for imaging myelin in vivo. Second, we investigate the use of a custom built low-repetition rate laser to substantially …