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Showing 1 to 1 of 1 for “"Non-zwitterionic GABA amide homodimers and heterod"”.
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Design and Syntheses of Potential Drugs Based on GABA(A) Receptor Pharmacophores
Numerous previous studies of GABAAR ligands have suggested that GABAAR agonists must be zwitterionic and feature an intercharge separation similar to that of GABA (approx. 4.7-6.0 Ã ). We have demonstrated that monomeric, homodimeric and heterodimeric non-zwitterionic GABA amides are partial, full, …