Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Non-steroidal anti-inflammatory drug"”.
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Advanced engineering of Fibrous Non-steroidal anti-inflammatory drug (NSAID) films for buccal application using Electrohydrodynamic Atomisation
… excipients. EHDA was employed to engineer NSAID drugs in fibre film form for buccal delivery. EHDA was selected to develop fibre film of Indomethacin, Diclofenac Sodium, Ketoprofen, and Piroxicam in cooperation of PVP, Ethocel, Methocel, HPMC, and Tween 80. Morphology of electrospun films were …
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Effect of a non-steroidal, anti-inflammatory drug (Indocin) on selected parameters of muscular function following concentric and eccentric work
… eccentric work. The action of an analgesic, anti-inflammatory drug (Indocin) on muscular soreness indicates it may be effective in accelerating recovery of muscle function after eccentric work. In the study reported herein the effects of Indocin on muscular performance, as evaluated on the …
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The nature, extent, and range of evidence of the premature constriction or closure of the ductus arteriosus in utero unrelated to known non-steroidal-anti-inflammatory drug exposure: a scoping review
… allows blood to bypass the fetal lungs. Non-steroidal anti-inflammatory drug (NSAID) use in late pregnancy can cause premature constriction or closure of the ductus arteriosus (PCDA), though cases also occur without NSAID exposure. Understanding non-NSAID-related PCDA (NNPCDA) is …
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Aspirin Resistance
Aspirin is a non-steroidal anti-inflammatory drug. It is used for the prevention of thrombo-embolism in patients at risk for getting them.Aspirin resistance is a term coined from people who take aspirin and still get thrombo-embolism. This discusses on the possible causes of aspirin resistance and …
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STUDY OF CLICK CHEMISTRY: WORKING TOWARDS ‘CLICKING’ A NON-STEROIDAL ANTI-INFLAMMATORY TO AN APOPTOSIS INHIBITOR Q-VD-OPH
… azides and terminal alkynes has contributed to drug discovery due to the high degree of dependability, efficiency, specificity and biocompatibility of the reactions and products. Using this well-known click chemistry reaction, a non-steroidal anti-inflammatory drug, naproxen, could possibly be …
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Assessing and Mediating Pain in Dairy Cows with Experimentally-Induced Clinical Mastitis
… a subcutaneous injection of either a non-steroidal anti-inflammatory drug (NSAID) (meloxicam; n=12) or placebo (n=12) was randomly allocated and administered using double-blind methods. Several behavioural, physiological and performance parameters were monitored throughout the study …
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The use of activity measures in combination with physiological factors as indicators of disease in dairy cattle
… the impact of flunixin meglumine (FM), a non-steroidal anti-inflammatory drug, on activity measures, dry matter intake (DMI) and milk production during experimentally induced Escherichia coli mastitis. A total of 24 primiparous and multiparous lactating dairy cows were challenged with …
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The Effects of Induced Polycystic Ovary Syndrome in NAG-1 Transgenic Mice
… hormonal imbalances, rather than diet. The human Non-Steroidal Anti-Inflammatory Drug Activated Gene (NAG-1) been shown to prevent diet-induced metabolic disorders and weight gain in mice. We hypothesized that the expression of NAG-1 may also prevent hormonal-induced metabolic disorders. To test …
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Role of The Immune System In The Modulation of The Mmr-Deficient Intestinal Stem Cell Niche
… cells. Our lab has also shown that naproxen, a non-steroidal anti-inflammatory drug (NSAID), has been effective at activating different subtypes of immune cells including macrophages. The purpose of this study was to understand how the immune cell compartment interacts with MMRd cells within the …
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Stimuli-responsive self-assembling materials comprising amphiphilic copolymers for localized remotely triggered therapeutic delivery
… traumatic wound deep within the body by external non-invasive stimulus could provide great long-term benefit to patients. In this work, we have examined systems consisting of or including amphiphilic copolymers towards deep-tissue externally triggered localized therapeutic delivery applications. …
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Photochemical, photophysical, and photobiological studies of zeolite guest-host complexes
… donor. In a second example, ketoprofen (a non-steroidal anti-inflammatory drug) was found to undergo intrazeolite photodecarboxylation to generate a benzylic carbanion. The lifetime of the zeolite-encapsulated carbanion was found to be fifty times longer than in solution. The enhanced …
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Developing methods to improve welfare in periparturient dairy cows and pre-weaned calves
… dairy cows and newborn calves. We administered a non-steroidal anti-inflammatory drug, meloxicam to periparturient dairy cattle. Treatments included administration prior to calving (MEL-PRE, n = 60), post-calving (MEL-POST, n = 69), or a negative control (CTL, n = 65). We measured the length of …
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Hydrogels for dermal applications
… photopolymerisation. The influence of ionic and non-ionic monomers, crosslinking systems, water and glycerol on the adhesive and dynamic mechanical behaviour of partially hydrated hydrogel systems was examined. The aim was to manipulate hydrogel behaviour to modify topical and transdermal …
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NSAIDs Modulate Morphine Transport at the Blood-Brain Barrier: A Role for P-glycoprotein
… demonstrated that experimental peripheral inflammatory pain (PIP), induced by subcutaneous plantar injection of λ-carrageenan in Sprague Dawley rats, results in increased expression and activity of the ATP-dependent efflux transporter P-glycoprotein (P-gp) that is endogenously expressed at …
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The Effect of Novel Anti-inflammatory Drugs on the Cyclooxygenase Enzymes and Recovery of Mucosal Barrier Function
The non-steroidal anti-inflammatory drugs (NSAIDs) are a large group of drugs that are commonly used for the treatment of pain and inflammation in the veterinary species. The NSAIDs inhibit the action of the cyclooxygenase (COX) enzymes, COX-1 and COX-2, to reduce the production of prostaglandins. …
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Repurposing non-antimicrobial drugs to treat multi-drug resistant bacterial and fungal infections
… and fungal resistance to conventional antimicrobials is a burgeoning global health epidemic that necessitates urgent action. Even more alarming, the development of new antimicrobials to treat these multidrug-resistant pathogens has not kept pace with the rapid emergence of resistance to …
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Epigallocatechin-3-gallate and tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer : Involvement of NSAID activated gene-1
… importance to investigate the efficacy of anti-oxidant and nonsteroidal anti-inflammatory drugs (NSAIDs) as chemopreventive agents. At present, the chemopreventive agents that have been most widely investigated as chemopreventive agents are NSAIDs and …
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Determination of an interaction between the DNA repair proteins MLH1 and sMBD4 and aspirin regulation of DNA repair gene and protein expression in colorectal cancer
… expression being susceptible to exposure to the non‐steroidal anti‐inflammatory drug, aspirin.
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