Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 113 for “"Non-essential"”.
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Characterisation of non-essential genes required for survival under conditions of DNA stress
… pombe (S. pombe) TopBP1 homologue that is essential for the initiation of DNA replication, DNA repair as well as the activation of DNA damage checkpoint signalling. We have modelled conditions of replication stress in the genetically tractable fission yeast, S. pombe using the hypomorphic …
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The Essential Role of the Non-Essential Amino Acid Asparagine in Lymphoid Malignancies
… and rely on exogenous sources for this non-essential amino acid. However, sensitivity to L-Asparaginase therapy is mitigated by the expression of the enzyme asparagine synthetase (ASNS), involved in de novo asparagine biosynthesis. We showed that this adaptive response requires two …
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Assessing the Effectiveness of Lockdowns and Mask Mandates on Reducing COVID-19 Infections in Essential Worker Populations
… Only a few, however, account for the role of "essential" workers, who must keep interacting face-to-face with others during a pandemic. In this work, we consider how these "essential" workers are disproportionately affected by the pandemic, and how they may act as a reservoir for the disease. …
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Foundations of Anti-caste Consciousness: Pandit Iyothee Thass, Tamil Buddhism, and the Marginalized in South India
… based on conscience and conviction. This phenomenon of religious conversion-social transformation is this study's focus. By combining archival research of Parayar's writings among Tamil Buddhists, as these Parayar, settled in Tamil Nadu and Karnataka, are called, I have attempted to understand …
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A Layered Ceiling: A Center for Ballroom Dance
… building is unnecessarily generous with the most essential elements and exaggerates non-essential elements in a way enhances their redundancy. Layered glulam ceilings cover the two main spaces and evoke the hidden structure of the sprung dance floor below. The ceiling is reflected in the pattern …
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Linking environmental variation across the Scottish Highlands with red deer (Cervus elaphus) trace element status, parasite burden, and skeletal morphometry
… variation in parasite prevalence or nutritional essential and non-essential trace/macro and toxic element status. Given the well-recognised effects of sub-lethal parasitism and sub-optimal nutrition on performance of ruminants (from an agricultural perspective; e.g., milk yield, growth rates), it …
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Effects of Heavy Metal Pollution on the Loggerhead Sea Turtle
… original studies on the blood concentrations of essential and non-essential heavy metals and their potential physiological correlates on the endangered loggerhead sea turtle (Caretta caretta). This work reflects analysis of archived samples collected in 2008 off the southeastern coast of the …
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Genome engineering and functional gene regulation tools for the study of malaria parasites
… The identification and characterization of essential functions for parasite survival are fundamental steps towards the creation of effective antimalarial therapies. In this work, we developed an integrated set of gene editing and functional gene regulation tools that enable the study of …
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Osteochondral allograft preservation in a serum-free chemically-defined media
… ITS, Sodium Pyruvate, L-ascorbic acid, and MEM Non-essential amino acids) and Test (DMEM) supplemented ITS+, Sodium Pyruvate, L-ascorbic acid, MEM Non-Essential amino acids, dexamethasone, boron, and TGF-[beta]3) media preparation at 4[degrees]C and 37[degrees]C. Media was changed and collected …
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Essence, Explanation and Kind-membership
… modal definition of ontological dependence, the essentialist definition promises to be sensitive to the direction in which specific dependence relation obtains. I argue that the promise is illusionary. The essentialist definition has the same defect facing the modal definition. The essence or …
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Evaluation of the effects of branched chain amino acids and corn-distillers dried grains by-products on the growth performance, carcass and meat quality characteristics of pigs
… to define the minimum CP level and whether non-essential amino acids become limiting in low crude protein diets for late finishing pigs. The results of this study demonstrated that late finishing pigs can be fed diets with 9.76% crude protein level supplemented with 0.32 % L-Lys HCL and …
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Morphological properties of poly (ethylene terephthalate) (PET) nanocomposites in relation to fracture toughness.
… the crystallization effects of MLS addition. Non isothermal crystallization kinetics showed that the melting temperature and crystallization temperature decrease as the MLS percent increases. This delayed crystallization along with the irregular spherulitic shape indicates hindered …
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Personality as a predictor of adherence to public health measures for controlling COVID-19 viral spread: The mediating roles of problem drinking and pandemic-related distress
Nonadherence to the public health guidelines implemented in response to COVID-19 is concerningly common, with some research implicating personality as a contributing factor. Thus, there is a need to examine the mechanisms behind personality-nonadherence associations. We examined the associations …
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Deconstructing Biopolitical and Performative Modes of Gender in Spanish Science Fiction
… studies. Gender identity is malleable and non-essential to the functions of reproduction and identity in every piece we examine. That idea is central to this thesis, which intends to demonstrate the potential of subversion through fantastical Spanish science fiction narratives.</p>
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Whole genome doubling confers unique genetic vulnerabilities on tumor cells
… integrating our genetic analysis with gene essentiality data acquired from Project Achilles, we identified gene dependencies in WGD+ cells. Moreover, we identified genes that are essential for the viability of WGD+ cancer cells, but non-essential to non-transformed diploid cells. We …
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Gathering Between Walls: A Catholic Church in 12 Mile, Kentucky
… concrete walls that would encompass all of the non-essential functions of the church, the space between the walls was freed up to be used as the body of the church where nothing but the Liturgy of the Eucharist would take place.
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Is Corporate Taxation Bad for the Environment? An Empirical Analysis of the Association between State-Level Taxation and Corporate Environmental Performance
… environmental efforts, which are often non-essential to a firm's operations, despite government incentives. Alternatively, higher tax rates may encourage firms to address environmental concerns due to the tax shield that these expenses provide and the relatively lower cost to …
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A developed metallomics method reveals the biochemical fate of Cd2+ and Hg species in erythrocyte lysate
… new insight into the bioinorganic chemistry of non-essential metal species in the human body. To this end, a metallomics method was developed to probe the interaction of Cd2+, Hg2+, CH3Hg+ and thimerosal in the erythrocyte based on the direct analysis of erythrocyte lysate by size exclusion …
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Strategic healthcare facilities management : a longitudinal case study in a private hospital group in the UK
… strategic attention needs to be given towards non-medical, butnot non-essential tasks. Effective management of facilities customer focusedand tailor made, seen as a process, with strategic planning and leadershipcontributes to the well-being of the patient. Here the public sector can learnfrom …
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The Shape of Seeing: An Ethnography of Phytolith Analysis
… to the next. In this model, analysts remove all non-essential context from one simulacrum, reinterpret the reduced form, and in doing so create a newly enacted simulacrum. Decontextualization and recontextualization occurs between each stage of analysis as well as over the course of a full cycle …
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