Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Nodularin"”.
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The Enantiospecific Total Syntheses of Adda and Nodularin
… acid (Adda) is a structural component of nodularin that has been reported to be necessary for biological activity. The complexity of Adda has hindered the completion of structure activity relationship (SAR) studies. This work has focused on development of procedures to synthesize Adda. As …
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An investigation into the biodegradation of peptide cyanotoxins (microcystins and nodularin) by novel gram-positive bacteria.
… secondary metabolites, microcystins (MC) and nodularin (NOD) have become common contaminants in most aquatic ecosystems over recent years presenting a hazard to animal and human health. Unfortunately, these chemically diverse peptide hepatotoxins remain a challenge to most conventional water …
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Effects of hydrothermal liquefaction on algal toxins from harmful algae blooms
… HTLaq (microcystins RR, LR, YR, LY, LA, LW, and nodularin) when operated at 300 °C for 30 minutes, which provided an average percent removal of 98% across the seven toxins tested. Additionally, optimization of temperatures was explored to determine how the HTL operating temperature affects the …
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Studies on secondary metabolites produced by actinomycetes and cyanobacteria
… studies compounds showed that the Adda unit of nodularin was derived from C-2, C-3 and the phenyl ring of scL-phenylalanine as well as acetate and methionine. A separate feeding experiment with (2-$\sp{13}$C) pyruvate suggested that the methylaspartate (MeAsp) unit could be derived from pyruvate …
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Monitoring and regulating cyanobacterial metabolites (microcystins and geosmin) in aquatic systems.
… are microcystins and their sister compound nodularin. The biological role of microcystins is poorly understood. A pheromonal effect was observed applying a novel stable isotope labelling (15N) method. Microcystin- LR has been shown to stimulate culture growth, limit microcystin synthesis, …
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A comparative study of the origins of cyanobacteria at Musina Water Treatment Plant using DNA fingerprints
… based on PCR by amplification of microcystin/nodularin and cylindrospermopsin polyketide synthetase genes. Most of the samples showed no amplification of the toxin genes. While two samples showed the amplification of cylindrospermopsin polyketide synthetase gene (Sand River and Nzhelele River …
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An investigation into factors influencing the production and degradation of microcystins.
… to degrade complex compounds like MCYST and nodularin. This thesis also highlights the need for developing an advance treatment approach, TiO2 photocatalysis has relatively recently been explored for industrial application of water management although the cost of using UV is prohibitive. …
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Evidence for functional drift of bacterial isolates in response to cyanobacterial microcystin-lr and multiple peptide degradation in paucibacter toxinivorans.
… is capable of degrading multiple MC variants, nodularin (NOD), anabaenopeptin-type peptides and human peptides. MC variants and NOD were found to be cleaved by hydrolysis indicating a single mechanism to be involved in their degradation. This is the first study to report partial elucidation of …
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Uptake and depuration of cyanotoxins in the common blue mussel Mytilus edulis.
… such as the hepatotoxins microcystin (MC) and nodularin (NOD). Their toxicity - in combination with the increasing global occurrence - has resulted in a drinking water guideline limit of 1 μg L-1 being issued by the World Health Organisation (WHO). However, these toxins are not only present in …
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Investigation of the production and isolation of bioactive compounds from cyanobacteria.
… late summer. Nodularia spp. are known to produce nodularins (NOD) and a range of other bioactive peptides such as spumigins and nodulopeptins, all of which have unclear function. In a recent study, three new nodulopeptins with molecular weight of 899, 901 and 917 were characterised from N. …