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Investigations into the role of RNA modification in the function of the c-Myc IRES

Goodacre, AlexanderUniversity of Cambridge2023

… cytoplasm and recent data have shown that m6A methylation alone, which occurs in the nucleus, is sufficient to promote internal ribosome entry. Therefore, a testable hypothesised is that the “nuclear” event required for IRES function is RNA modification. Prior data from a yeast 3 Hybrid screen …

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