Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"Nkx2.5"”.
-
Role genu Nkx2.5 v morfogenezi a elektrofyziologii srdce u myši
Role genu Nkx2.5 v morfogenezi a elektrofyziologii srdce u myši Praha 2016 Bc. Peter Hámor ABSTRAKT Cieľom tejto práce je skúmanie vplyvu dávkovania génu Nkx2.5 na elektrofyziológiu srdca myší v prenatálnom období vývoja. Hlavnou úlohou je hľadanie rozdielov vo vedení elektrického vzruchu v srdci …
-
Transcriptional Profiling of Early Cardiac Development
… network of a key cardiac regulator, Nkx2.5. I identified transcripts misexpressed during the early development of Nkx2.5 null embryos, including the Nkx2.5 transcriptional targets ETSrelated transcription factor 71 and vascular cell adhesion molecule. Lastly, I characterized …
-
An investigation into a role for follistatin in early cardiogenesis in Xenopus Laevis
… in addition to the known inhibition of Nkx2.5 expression and BMP signaling.
-
Zebrafish Cardiac Development Requires a Conserved Secondary Heart Field
… birds and mammals are conserved in teleosts, as Nkx2.5 and Nkx2.7 as well as Fgf8 regulate Bmp signaling in the zebrafish heart fields. Additionally, the transcription factor Tbx1 and the Sonic hedgehog pathway are necessary for normal development of the zebrafish arterial pole.</p>
-
Tbx20 - Ein essentieller Regulator der Entwicklung des atrioventrikulären Kanals im Zebrafisch
… transkriptorische Aktivität von Tbx20 mit Nkx2.5, Gata5 und Tbx5 reguliert wird und dass bmp4 ein direktes Zielgen von Tbx20 darstellt. Des Weiteren wurde im Rahmen dieser Arbeit im Zebrafisch eine zweite Isoform von Tbx20, Tbx20b, isoliert, die nicht die Entwicklung des AVCs oder des …
-
Regulation and patterning of cell differentiation and pluripotency
… and reduced expression of troponin I and Nkx2.5) along with the continued expression of cardiac markers (α-actin, connexin-43, and calcium transients). After the immortalization was reversed, cells returned to their differentiated state, as evidenced by molecular and functional properties …