Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Nkd1"”.
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Regulation of Wnt signalling in ovarian cancer and immune cells
… negative regulators of the Wnt pathway, Dkk1 and Nkd1, with decreased immune infiltration in ovarian cancers. To interrogate the functional importance of these negative regulators further, I knocked out and expressed Dkk1 and Nkd1 in murine ovarian cancer models ID8 p53 / and UPK10. Overexpression …
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Mechanisms of molecular switching in the Wnt signal transduction pathway
Wnt signalling is a critical cellular communication pathway controlling cell fate in all metazoan organisms. Timely activation of this pathway is crucial to coordinate development, control homeostasis of adult tissues, and to avoid cancer. Wnt signal transduction depends primarily on the activities …