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Showing 1 to 19 of 19 for “"Nitrosamine"”.
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Activated carbon catalyzed nitrosamine formation via amine nitrosation
Nitrosamines have garnered increasing attention from researchers and policy makers in recent years due to potential human health implications associated with their unintentional formation in water and wastewater treatment facilities. This work addresses a crucial nitrosamine formation pathway …
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Total N-nitrosamine Precursor Adsorption with Carbon Nanotubes: Elucidating Controlling Physiochemical Properties and Developing a Size-Resolved Precursor Surrogate
… (THMs), dihaloacetonitriles (DHANs), and N-nitrosamines – during water treatment may also increase. N-nitrosamines may comprise the bulk of the chronic toxicity in treated drinking waters despite forming at low ng/L levels. This research seeks to elucidate physicochemical properties of …
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Biofilm-related Materials as Total N-nitrosamine (TONO) Precursors and Hydroxylamine-based Interferences in TONO and N-nitrosodimethylamine (NDMA) Measurements
… this study, a chemiluminescence-based total N-nitrosamine (TONO) assay was adapted to include a solid-phase extraction (SPE) step to assess the role of biologically derived materials as N-nitrosamine precursors. Methanol was determined to be a suitable solvent for the SPE-TONO assay, with …
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Unraveling the Effects of Nicotine-Derived Nitrosamine Ketone (NNK) on Healthy and Neurodegenerative Brain via Intravital Imaging and Multiscale Ex Vivo Imaging Approaches.
… stroke, and multiple sclerosis. Nicotine-derived nitrosamine ketone (NNK) is a nicotine metabolite produced within the tobacco plant from combustion and metabolic breakdown of nicotine. Extensive cancer literature has established NNK as an important component of CS resulting in DNA mutation and …
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Drinking water disinfection by-products detection, formation and the precursors removal study
… of THMs and HAAs will form. In addition, if N-nitrosamine precursors are present, highly toxic N-nitrosamines may form during water treatment process. In the third part of this dissertation, zeolites and activated carbon were examined for ammonia and N-nitrosamine precursors removal when …
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Επίδρση της Ν.Ν.- Διμεθυλο - Νιτρωδοαμίνη στο μεταβολισμό του RNA σε ΜΥΕΣ C57BL
… SINGLE DOSE OF THE HEPATOCARCINOGEN DIMETHYL-N- NITROSAMINETO MALE C57B1 MICE CAUSES AN INHIBITION OF HN-RNA SYNTHESIS. THE EXTENT OF THE INHIBITION DEPENDS ON THE DOSE ADIMINISTERED: THUS 4 HOURS AFTER THE ADMINISTRATION OF A DOSE OF 40MG/KG DIMETHYLNITROSAMINE, THE INHIBITION OF HNRNA SYNTHESIS …
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ΜΕΛΕΤΗ ΑΝΤΙΔΡΑΣΕΩΝ ΕΤΕΡΟΚΥΚΛΙΚΩΝ ΑΡΩΜΑΤΙΚΩΝ ΝΙΤΡΩΔΑΜΙΝΩΝ
… [AMINE] [NITROUS ACID] HO. (I) THE RESPECTIVE NITROSAMINE FORMED IS EASILY DENITROSATED UNDER THE EXPERIMENTAL CONDITIONS. THE VALUE OF K3 IS COMPATIBLE TO THAT OF THE NITROSATION OF 4-METHYLAMINO- PYRIDINE. AN EXAMINATION OF THE K3 VALUES FOR SOME AMINES INDICATES THAT THE NITROSATING AGENT, …
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Modulatory Effects of Citrus Flavonoids Towards the Metabolism and Mutagenicity of Environmental Carcinogens
… amines (HCA’s) and the tobacco-specific nitrosamine NNK generally require internal enzymatic activation. This activation occurs via cytochrome P450 (CYP) enzymes and leads to metabolites that bind to human DNA which may in turn cause mutations which may then in turn lead to …
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Modelling, Simulation, and Optimisation of Reverse Osmosis Process with Application in Wastewater Treatment and Food Processing
… of toxic compounds such as chlorophenol, N-nitrosamine, etc. from wastewater. The effect of several operating parameters such as feed pressure, concentration, flow rate and temperature, on the performance of RO process are evaluated. Also, suitability of a number of different RO …
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Ndma Formation During Chloramination: Temporospatial Distribution Of Ndma Precursors, The Effect Of Lime Softening Treatment, And Precursor Identification Via Non-Targeted Analysis
… carcinogenicity and toxicity. NDMA and other nitrosamine precursors are compounds containing secondary, tertiary, and quaternary amines, which can be released from diverse sources into the surface waters. There is still much to be understood, however, about the fate of these precursors in …
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Kostnaðarvirknigreining á lögleiðingu sænsks munntóbaks
… með lágu magni krabbameinsvaldandi efna (e. Low-nitrosamine smokeless tobacco product). Áhugi hefur vaknað meðal fræðimanna um möguleika þess að nota sænskt munntóbak til að draga úr reykingum. Á Íslandi er innflutningur og sala á munntóbaki bönnuð lögum samkvæmt. Markmið þessarar ritgerðar er að …
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Occurrence, monitoring and removal of drinking water contaminants by advanced technologies
… are raised as MCA disinfection has been linked N-nitrosamine formation. N-nitrosamines are a group of nitrogenous DBPs (N-DBPs) which are highly carcinogenic in comparison to regulated DBPs (THMs and HAAs, generated by FC disinfection). Also in the forefront of drinking water concerns are other …
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Environmental considerations for interactions between agricultural herbicides and nitrogen fertilizers in water
… Another potential result is the formation of nitrosamines. Nitrosamines, which can be carcinogenic, mutagenic, and teratogenic, are a product of xenobiotic reactions and pose an equal or greater risk to the environment and human health than the parent compounds. The combination of nitrosatable …
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Multivariate Analysis of Disinfection By-products Formation in Drinking Water Distribution Systems
… for reducing one class of chloramination DBP (N-nitrosamine) formation in a lab-scale DWDS under various conditions. Findings drawn from this research will provide guidance for water utilities to design suitable disinfection strategies for improved management of disinfectant decay and DBP …
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Leveraging the Photochemistry of N-Nitrosamines for Their Aqueous Detection, and Development of a Novel Hemi-Iptycene for Porous Polymers
N-Nitrosamines are a class of compounds known for both the potent carcinogenicity of many of its members, and for their widespread occurrence in the human environment. Consequently, the development of methods for their detection is an active area of research. Chapter 1 provides an introduction to …
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Systematic Approach to Degradation Studies in Catalyst Based Amine CO2 Capture Process
… BEA/AMP as it addresses the problem of potential nitrosamine and nitramine formation. Two basic catalysts, proprietary absorber catalyst (PAC), and activated carbon spheres (ACS) and one acid catalyst, PDC were also synthesized, characterized, screened, and compared with the existing basic …
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The Effects of Time-Restricted Feeding on Early Phases of Liver and Colon Carcinogenesis
… female rats. For liver carcinogenesis, diethyl nitrosamine (DENA) was administered as a single dose to initiate tumor development. For colon carcinogenesis, azoxymethane (AOM) was administered in 2 doses for two consecutive weeks to initiate the process. Following the carcinogen administration, …
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The Contribution of Environmental Cues to Early Squamous Tumour Formation in the Upper Gastrointestinal Tract
… mouse model based on the exposure to di-ethyl-nitrosamine (DEN), a carcinogen found in cigarette smoke. This model induces the formation of pre-neoplastic squamous tumours in the upper gastrointestinal tract that can be detected as early as 10 cells in size and sporadically progress towards …