Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Nitrofurantoin"”.
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Pharmaceutical applications and crystal structures of trehalose and its derivatives.
… strategies using model drugs (ascorbic acid and nitrofurantoin) were prospectively developed and tested for unwanted stability problems or incompatibilities between active compound and proposed excipients. A stability indicating HPLC assay (using an ODS C8 column), to quantify ascorbic acid …
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Analogues of Nitrofuran Antibiotics are Potent GroEL/ES Pro-drug Inhibitors with Efficacy against Enterococcus Faecium, Staphylococcus Aureus, and Escherichia Coli
… antibiotics – nitroxoline, nifuroxazide, and nitrofurantoin – prompted me to develop two series of hydroxyquinoline and nitrofuran-based analogs. I then assessed these compounds’ abilities to inhibit in vitro GroEL/ES activity, as well as to selectively target ESKAPE/E. coli bacteria over …
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IN VITRO ΚΑΙ IN VIVO ΜΕΛΕΤΕΣ ΤΗΣ ΕΠΙΔΡΑΣΗΣ ΤΩΝ ΠΡΩΤΕΙΝΩΝ ΣΤΗ ΔΙΑΛΥΤΟΠΟΙΗΣΗ ΚΑΙ ΑΠΟΡΡΟΦΗΣΗ ΔΙΚΟΥΜΑΡΟΛΗΣ ΝΙΤΡΟΦΟΥΡΑΝΤΟΙΝΗΣ ΚΑΙ ΣΟΥΛΦΑΜΕΘΙΖΟΛΗΣ
… THEY ARE MET IN FOODSTUFFS) WERE INVESTIGATED. NITROFURANTOIN, DICUMAROL AND SULFAMETHIZOLE WERE CHOSEN AS MODEL DRUGS. BOVINE SERUM ALBUMIN AND CASEIN WERE USED AS MODEL PROTEINS. THE IN VITRO STUDIES INCLUDED DISSOLUTION AND TRANSPORT OF ALL DRUGS THOUGH DIALYSIS MEMBRANES. MOREOVER PROTEIN …
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Synergistic Effects of Monoculture Biofilm Dispersion and Antibiotic Treatment
… Antibiotics selected were tobramycin and nitrofurantoin due to their clinical use against urinary tract infections. Both potential dispersal agents showed the most effect when used to treat P. aeruginosa biofilms cultured in Luria-Bertani broth (LB). There was no increased dispersal or …
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Bacteriology and antibiotic sensitivity patterns of urine in urology patients with indwelling urinary catheters at the University Teaching Hospital in Lusaka, Zambia.
… were least resistant to amikacin, imepenem, nitrofurantoin, and gentamycin. Acetinobacter and Citrobacter species were also highly resistant to the above drugs with nitrofurantoin in addition but least resistance to Ampicillin. The study revealed that there is a high prevalence of catheter …
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Evaluation of HB&L Automated System for Rapid Diagnosis of Urinary Tract Infections // Оценка на автоматизираната система HB&L за бърза диагностика на инфекции на уринарния тракт
… in outpatient practice was studied: fosfomycin, nitrofurantoin, and 5-nitroxoline. A high concordance of results was demonstrated. The system showed high specificity, sensitivity, and positive and negative predictive values. Based on the results, a working algorithm for the accurate and rapid …
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Spektrum und Resistenzmuster uropathogener Keime an der Freiburger Universitäts-Kinderklinik
… Sehr gut bewährt haben sich hingegen Nitrofurantoin und Cephalosporinen der 3. Generation. Bei Kindern mit Harntransportstörungen ist eine Kombination aus Aminoglykosiden und Aminopenicillinen sinnvoll. Um die Entwicklung der Resistenzmuster genau im Auge zu behalten, bedarf es …
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Charakterisierung neuer Zielstrukturen für die Antibiotikatherapie gegen Staphylococcus aureus und Entwicklung eines konditionalen In-vivo-Expressionssystems
… oxidativen Stress, verursacht von Diamide oder Nitrofurantoin, und durch Ethanol induziert wird. Ethanol und oxidativer Stress führt zu Denaturierung von Proteinen. NfrA könnte an der Reparatur geschädigter Proteine beteiligt sein. Die Induktion von nfrA in S. aureus erfolgt unabhängig vom …
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A study on the detection of extended spectrum beta lactamase producers and class I intergrons in e. coli isolates from urinary tract infected patients at UTH.
… while no resistance (0%) was detected to Nitrofurantoin. All the ESBL producers had MDR (at least 30%) patterns. None of the risk factors was statistically significant in this study. This study detected the presence of ESBLs and class I integrons in MDR E. coli in UTIs at the University …
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A study on the detection of extended spectrum beta lactamase producers and class I intergrons in e. coli isolates from urinary tract infected patients at UTH.
… while no resistance (0%) was detected to Nitrofurantoin. All the ESBL producers had MDR (at least 30%) patterns. None of the risk factors was statistically significant in this study. This study detected the presence of ESBLs and class I integrons in MDR E. coli in UTIs at the University …
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Outpatient Antibiotic Prescribing, Dispensing and Susceptibility Testing in a Primary Care Spinal Cord Injury Cohort
… more likely to prescribe fluoroquinolone, than nitrofurantoin for UTIs. Study 3 identifies who prescribed outpatient antibiotics based on physician speciality for 320 individuals with SCI, who receive support from a drug benefit program. Nearly 60% of antibiotics were prescribed by physicians in …
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Characterisation of the Mycoplasm mycoides subspecies mycoides Small Colony from Kazungula District of Zambia, a Contagious Bovine Pleuropnueumonia Outbreak Area
… were susceptible to growth inhibition effects of nitrofurantoin,tetracycline, gentamycin, erythromycin, co-trimoxazole and tylosin except one from Kazungula district which resisted all the antibiotic effects other than that of tylosin. IV The isolates were further characterised using Restriction …
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Primary care antimicrobial stewardship: Impact on prescribing and resistance
… other antimicrobials (amoxicillin, trimethoprim, nitrofurantoin, and doxycycline), and significant increases in coliform bacteraemia resistance to amoxicillin were also observed.<b><br/></b><b><br/></b><b>Conclusions:</b> Most types of stewardship intervention reduce antimicrobial prescribing in …
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Antimicrobial resistance among pregnant women with urinary tract infections attending antenatal clinic at Levy Mwanawasa university teaching hospital Lusaka, Zambia
… chloramphenicol (20%), ciprofloxacin (30.5%) and nitrofurantoin (40%). There were no significant predictor variables to AMR. Conclusion: Generally, a much higher prevalence of UTI than most studies undertaken has been found in this study, indicative of the level of menace urinary tract infections. …
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Detection of Vancomycin resistant Enterococci from clinical specimens at University Teaching Hospitals
… and Clindamycin, with none being resistant to nitrofurantoin. More enterococci were isolated from urine compared to pus and blood, with most patients affected being aged between 28 and 46. More women were affected as compared to men. Brilliance chromogenic media was accurate in detection of …
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Antimicrobial resistance among pregnant women with urinary tract infections attending antenatal clinic at Levy Mwanawasa university teaching hospital Lusaka, Zambia
… chloramphenicol (20%), ciprofloxacin (30.5%) and nitrofurantoin (40%). There were no significant predictor variables to AMR. Conclusion: Generally, a much higher prevalence of UTI than most studies undertaken has been found in this study, indicative of the level of menace urinary tract infections. …
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Detection of Vancomycin resistant Enterococci from clinical specimens at University Teaching Hospitals
… and Clindamycin, with none being resistant to nitrofurantoin. More enterococci were isolated from urine compared to pus and blood, with most patients affected being aged between 28 and 46. More women were affected as compared to men. Brilliance chromogenic media was accurate in detection of …
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Urinary tract infection in children at Victoria Hospital, a district hospital in Cape Town, South Africa
… (88%), ciprofloxacin (94%), gentamicin (86%) and nitrofurantoin (90%). Eleven (12%) isolates were extended spectrum beta lactamase-producing organisms but no carbapenem-resistant organisms were isolated. Conclusion: Although this study did not evaluate clinical outcomes of children, the AST …
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Determination of the occurrence, virulence genes, and antimicrobial resistance profiles of enterococcus faecalis and enterococcus faecium isolated from poultry of Chongwe, Lusaka, Kitwe, and Ndola districts, farmworkers from the Copperbelt province poultry farms and clinical specimens from Kitwe teaching hospital in Zambia.
… chloramphenicol, ciprofloxacin, erythromycin, nitrofurantoin, penicillin, tetracycline, vancomycin combination. The frequently detected resistance genes in E. faecalis were tetK and tetM from Kitwe and Ndola, respectively, and in E. faecium, it was aac(6′)-Ieaph(2″)-LA and ermB from Kitwe, and …