Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Nitric Oxide Synthase 2"”.
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The Role of Inflammation and Nitric Oxide Synthase 2 in Triple-Negative Breast Cancer Metastasis
High expression of inflammatory marker nitric oxide synthase 2 (NOS2) expression in tumor cells indicates poor prognosis, poor survival, and chemotherapeutic resistance in triple-negative breast cancer (TNBC) patients. The tumor microenvironment (TME) comprises various cell types that play a role …
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Novel pathways of human host defence against Mycobacterium tuberculosis
… plays in the H3K27me3 epigenetic suppression of nitric oxide (NO•) production downstream of Nitric Oxide Synthase 2 (NOS2) transcription in human macrophages. I determined that the inhibition of NO• production could be reversed through pre-infection treatment of the macrophage with GSK126, an …
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IMPACT OF L-ARGININE TRANSPORTATION ON MYELOID-DERIVED SUPPRESSOR CELL FUNCTION
… of L-Arginine (L-Arg) by Arginase 1 (ARG1) and nitric oxide synthase 2 (NOS2). Therefore, we hypothesized that restricting MDSC uptake of L-Arg is a critical control point to modulate their suppressor activity. To this end, we have identified the mechanisms by which extracellular L-Arg is …