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Showing 1 to 20 of 57 for “"Nitration"”.
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The nitration of cotton cloth
… a cellulose nitrate, cloth, (by the direct nitration of cotton cloth) which would be suitable for use in powder bags. Such a product must have a rapid rate of combustion, a very small amount of ash, and a tensile strength which would meet Government requirements for powder bags. The results …
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Peroxynitrite-mediated oxidations: nitration and nitrosation
… gives N-nitromorpholine and N-nitrosomorpholine. Nitration and nitrosation of morpholine are catalyzed by low levels of CO<sub>2</sub>; however, excess CO<sub>2</sub> dramatically reduces the yields of nitrosation but not nitration, and the combined yields of the products are about the same under …
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Probing Isoforms of the Prion Protein through Tyrosine Nitration
… of the disease related isoforms are unknown. The nitration labeling patterns of three PrP isoforms with peroxynitrite and tetranitromethane, as detected by mass spectrometry, are reported. Two conserved tyrosine residues (tyrosines 149 and 150) are not labeled by either reagent in the normal …
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Probing Isoforms of the Prion Protein through Tyrosine Nitration
… of the disease related isoforms are unknown. The nitration labeling patterns of three PrP isoforms with peroxynitrite and tetranitromethane, as detected by mass spectrometry, are reported. Two conserved tyrosine residues (tyrosines 149 and 150) are not labeled by either reagent in the normal …
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H2O2-mediated oxidation and nitration enhances DNA binding capacity / DNA repair via up-regulated epidermal wild-type p53 in vitiligo.
… show for the first time the presence of abundant nitration of p53 protein in vitiligo. In addition using purified p53 from E. coli strain (BL21/DE3) and mutant p53 protein from HT-29 cells (colon cancer cells), we show that nitration takes place in a dose and time dependent manner. On this basis …
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Tyrosine nitration and altered protein pool levels of glyceraldehyde-3-phosphate dehydrogenase following ischemia/reperfusion: The influence of aging in glycolytic skeletal muscle
… transcription. Finally, we examined tyrosine nitration. A\r\nvii\r\nspot selected following 2D gel electrophoresis and nitrotyrosine western blotting of\r\nyoung and old muscle lysate was identified as GAPDH by mass spectrometry. We\r\ncompared tyrosine nitration over the time course of …
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CAVEOLAE AS SPATIO-TEMPORAL COMPARTMENTS FOR ROS/RNS GENERATION AND NITROXIDATIVE STRESS SIGNALING
… compartments for ROS/RNS generation, tyrosine nitration of proteins, b) platforms to propagate localized nitroxidative signaling in inducing endothelial cell activation and dysfunction (ICAM-1, VCAM-1 expression), and c) intracellular redox signaling endosomes to regulate adhesion molecule …
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A Contribution to the Chemistry of 1,2,3-BENZOTHIADIAZOLE
… of systems containing the 1,2,5-thia;diazole The nitration of 1,2,5-henzothiadiazole and the chlorination, iodination, diazo-coupling, and nitration of the four amino-l,2,3--henzothiadia2oles and some of their N~acyl derivatives have been studied. Differences in the 300-350 region of the spectra …
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Development of novel nutrapharmaceuticals combining the anti-oxidant and anti-inflammatory properties of n-3 fatty acids with a nitric oxide donor: a potential new preventative strategy for heart disease.
… and full characterisation has been achieved. The nitration stage of synthesis was achieved using tert-butyl nitrite and 'fuming' NO as the nitrating agents. Successful nitration was determined by MS analysis and by use of the Griess reaction as a colourimetric test to determine the ability of the …
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Investigation of amyloid-β aggregates derived from light-triggered nitration: relevance for Alzheimer’s disease [Indagine sugli aggregati di amiloide-β derivanti dalla nitrazione indotta dalla luce: rilevanza per la malattia di Alzheimer]
La malattia di Alzheimer (AD) è caratterizzata da una complessa eterogeneità molecolare, in cui diverse forme di amiloide-β (Aβ) e modifiche post-traduzionali (PTMs) contribuiscono alla genesi di diversi percorsi di aggregazione, risposte infiammatorie e risultati clinici. Tra le PTMs, la …
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Nitrations of viscose rayon
… it seems that any continuous type of acidic nitration of viscose rayon for use in powder bags or guncotton would be highly impractical.
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Characterization of cellulose esters via GPC/FT-IR
… was observed to be dependent upon the degree of nitration of the cellulose nitrate. This absorption was found to be due to steric hindrance between secondary nitrate groups on the C₂ and C₃ sites. The infrared absorptions of cellulose acetate butyrates in THF, acetonitrile, and methylene chloride …
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Preparation of azidobrevianamide A and synthetic and biological studies of tetrazomine
… (+)-brevianamide A. The synthesis involved nitration, reduction to the amine, formation of the diazonium ion, and reaction with azide ion. These compounds might be of potential use as photo-affinity labeling agents for the isolation of a potential enzyme catalyzing a Diels-Alder reaction in …
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Post-Translational Modification of Proteins via Ambient Air Pollutants and Endogenous Reactive Species
… study was further conducted (Chapter 4) and the nitration degree, or NTyr concentration, of the exposed samples was correlated with air pollutant concentrations and atmospheric conditions. The formation of DiTyr in the exposed samples was also detected in this study, representing the first time …
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Physical Mechanisms of Ca-ATPase Regulation in the Heart
… diseases of the heart. In the heart, age-based nitration of the Ca-ATPase inhibits Ca²⁺ transport activity but the physical mechanism by which nitration inhibits Ca-ATPase activity is not understood. Conversely, nitroxyl (HNO), a new candidate for drug therapy for congestive heart failure (CHF), …
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Profiling the Organic Emissions from a Light-Duty Direct Injection Diesel Engine over a range of Speeds and Loads
… of primary emissions. In the case of nitro-PAC, nitration has been proposed to occur by free radical processes between PAH and oxides of nitrogen, NO,, within the chamber and by electrophilic substitution of PAH surviving combustion by nitrogen dioxide and nitric acid, via the nitronium ion. The …
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A framework for integrating chemistry and process synthesis in the analysis of pathways for chemical manufacture
… also presents a flow sheet for mixed-acid batch nitration, reaction pathways for making various substituted benzenes, a general MILP formulation for evaluating and comparing chemical manufacturing pathways, and a review and analysis of different approaches to multiobjective decision-making. (UMI …
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Enantioselective synthesis of pretomanid & investigations of Raman spectroscopy for through-tube monitoring of reactions
… epoxide-opening cyclization and late-stage nitration. This route offers a new strategy to access the core of pretomanid and avoids the necessity of the explosive starting material. Chapter 2: Investigations of Raman Spectroscopy for Through-Tube Monitoring of Reactions [color illustrations] …
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I. Solubility and blend studies of nitrocellulose II. Relaxation properties of thin film coatings: the role of surface topography
… of nitrocellulose were determined at a series of nitration levels which were used to guide the selection of suitable plasticizers for nitrocellulose films. Subsequent dynamic mechanical experiments were then used to evaluate the effectiveness of the blend formulations in broadening the glass …
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Impact of Post-Synthesis Modification of Nanoporous Organic Frameworks on Selective Carbon Dioxide Capture
… g-1). Post-synthesis modification of NPOF-4 by nitration afforded (NPOF-4-NO2) and subsequent reduction resulted in an amine-functionalized framework (NPOF-4-NH2) that exhibits improved gas storage capacities and high CO2/N2 (139) and CO2/CH4 (15) selectivities compared to NPOF-4 under ambient …
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