Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Nigericin"”.
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The functional motifs for nucleocytoplasmic shuttling of C-terminal fragment of c-Met : A novel "pH-dependent' nuclear localization signal
… Indeed, decreasing the cytosolic pH either with nigericin, a Na+/H+ exchanger or low pH KRB (pH=6.5) buffer significantly increased the level of nuclear c-Met and the interaction of the c-Met fragment with importin β, indicating that low cytosolic pH itself enhanced nuclear translocation of …
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The effects of E-cigarettes on pulmonary inflammation and inflammasome activation
… with classical inflammasome activators, LPS and Nigericin, the simultaneous addition of E-vapour with these signals reduced inflammasome activation. Analysis of BAL from E-cigarette users and smokers after LPS inhalation showed a similar inflammatory profile as measured by inflammatory cytokine …
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Anatomical, developmental and physiological aspects of silica in wheat
… erythrosin B) and ionophores (nigericin, FCCP). The data suggests that functional ATPases and a proton gradient are required for silica uptake. Transport into the xylem and uptake at the root surface may be differentially affected by the inhibitors.
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Der Proteintransport in Rhodobacter capsulatus und Escherichia coli über das Tat-Transportsystem
… bedingt. Durch Verwendung des K+/H+-Ionophors Nigericin wurde dieses Ergebnis bestätigt. Da durch das K+-Ionophor Valinomycin die Translokation von pSufI verringert wurde, wurde die Abhängigkeit vom elektrochemischen Membranpotential gezeigt. <br>Mit Hilfe eines chemischen und eines …
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Entamoeba histolytica-induced Activation of Caspase-4 Regulates Gasdermin D Cleavage to Mediate IL-1β Secretion in Macrophages
… marked contrast to the positive control, LPS + Nigericin that induced high expression of caspase-1, enhanced GSDMD cleavage, IL-1β secretion, and massive pyroptotic cell death. Edman degradation and in vitro caspase cleavage assays showed that caspase-4 cleaved GSDMD at the same position as …
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Molecular characterization of cation-coupled transporters: the H+-coupled Mg2+-citrate transporter, CitM, and the Na+/sulfate cotransporter, hNaSi-1
… proton gradient, including FCCP, TCC and nigericin, suggesting a proton-coupled transport. Valinomycin did not affect the uptake by CitM, supporting an electroneutral transport model in which one proton is coupled to the uptake of one complex of (Mg2+-citrate)1-. \r\n\r\nThe low affinity …
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Ion channel modulation during Chlamydia trachomatis development
… the infection cycle using the K+ ionophore nigericin or sulfonylurea inhibitor glibenclamide promotes bacterial persistence. While these observations revealed an essential role for K+ during infection, the focus was the early replicative phase of the cycle. Since mid- cycle and late-cycle …
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Elucidating the Role of Toxin-Induced Microbial Stress Responses in Biological Wastewater Treatment Process Upset
… (DTT). The polyether ionophore antibiotic, nigericin, was used to artificially stimulate K+ efflux from S. capsulata and activated sludge cultures. Thus, glutathione-gated K+ efflux (GGKE) activity may cause K+ release from the cytoplasm of activated sludge bacteria into the floc structure …
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Inflammasome signalling during Salmonella Typhimurium infection
The innate immune system is the first line of defence against infection. It is comprised of physicochemical barriers and a variety of cell types including macrophages and dendritic cells. Pathogens express specific pathogen associated molecular patterns (PAMP) which are recognised by pattern …