Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Nigella sativa"”.
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Isolation and Characterization of Active Ingredients from Nigella Sativa for Antibacterial Screening.
… of total extract from the seeds of <em>Nigella sativa</em> (Black cumin). In attempts to identify the active ingredients in this extract, the seeds were extracted with hexane. The volatile oil obtained from the crude extract was shown to contain at least three distinct compounds, …
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Pengaruh pemberian ekstrak biji jintan hitam (Nigella sativa Linn.) terhadap kadar asam urat darah dan gambaran histologi ginjal mencit (Mus musculus) hiperurisemia
… bahwa pemberian ekstrak biji jintan hitam (Nigella sativa Linn.) berpengaruh terhadap kadar asam urat darah mencit (Mus musculus), namun belum memperlihatkan pengaruh yang signifikan dalam memperbaiki kerusakan glumerolus ginjal. Dosis yang efektif mempengaruhi kadar asam urat darah adalah …
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Pengaruh pemberian ekstrak biji jintan hitam (Nigella sativa Linn.) terhadap kadar enzim transaminase hepar (GPT dan SGPT) pada tikus (Rattus norvegicus) diabetes
… causes of level of oxidan in body increases. Nigella sativa contain antioxidant compounds that reduce oxidant. The purpose of this experiment was to determine the effect of Nigella sativa extract of transaminase levels in diabetic rats liver. These was an experiment study using a Randomized …
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Pengaruh pemberian ekstrak biji jintan hitam (Nigella sativa Linn.) terhadap kadar asam urat dalam urin dan gambaran histologi hepar pada mencit (Mus musculus) jantan
INDONESIA: Jintan hitam (Nigella sativa Linn.) adalah tanaman yang mengandung antioksidan berupa senyawa timokuinon. Senyawa ini mempunyai kemampuan untuk membantu pengeluaran asam urat lewat urin dan memiliki efek hepatoprotektor sehingga diharapkan dapat menjadi alternatif untuk mengatasi …
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Pengaruh pemberian ekstrak etanol jintan hitam (Nigella sativa) terhadap integritas membran spermatozoa dan kadar malondialdehyde (MDA) epididimis mencit yang dipapar timbal (Pb) esetat peroral
INDONESIA: Pb asetat merupakan salah satu sumber ROS yang dapat mengakibatkan peroksidasi lipid dan peningkatan kadar malondialdehyde (MDA) yang ditimbulkan oleh stress oksidatif. Salah satu yang ditimbulkan oleh stress oksidatif adalah terganggunya proses maturasi spermatozoa di dalam epididimis. …
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The synthesis of novel indazole alkaloids with potential medicinal properties.
The black seeds of Nigella sativa Lin. are universally accepted as a panacea. In particular the black seed oil extract has been shown to have bronchodilatory, antidiabetic, antibacterial, antifungal, analgesic, anti-inflammatory, and immunopotentiang activities. Four principal alkaloids Nigellicine …
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Efficacy of tamoxifen and thymoquinone on tumor development, lipid peroxidation, and total antioxidant capacity in DMBA induced mammary carcinoma in female Sprague-Dawley rats
… and lipid peroxidation. Thymoquinone (TQ), from Nigella sativa seeds, is a Middle East natural medicine and it has been used to treat a number of diseases, including cancer. The aim of my study was to investigate the effect of TQ and TAM on tumor development, lipid peroxidation level, and total …
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Thymoquinone decreases oxidative DNA damage (8-OHdG) in DMBA treated female Sprague Dawley rats
… Thymoquinone (TQ), the main active ingredient of Nigella sativa, or Black seeds, is used in the Middle East for treatment of several diseases, especially cancer. The aim of my research was to investigate the role of thymoquinone in improving 8-OHdG and GSH compared with tamoxifen in female Sprague …
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Broad-spectrum antivirals against coronavirus using natural products and drug repurposing strategies
… antiviral discovery, with a focus on Nigella sativa (black seed) oils. While direct contact assays revealed limited antiviral efficacy, vapour-phase diffusion of the oils significantly reduced coronavirus infectivity. Chemical analysis identified volatile terpenes and phenolic …
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Amelioration of the chronic relapsing experimental allergic encephalomyelitis (CR-EAE) using thymoquinone
… of Thymoquinone (TQ) a constituent of oil of Nigella Sativa also known as black seed. Thirty female mice strain C57BL/6J between 6 to 12 weeks of age were placed into 3 groups of 10 and MOG was used subcutaneously (s.c) to induce EAE. Group A, the control group. Group B, received MOG (s.c) and …
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Thymoquinone is a Novel Ligand which Activates Neu4 Sialidase to Promote a Pro-Inflammatory Response
… oil component of black seed oil (derived from Nigella sativa), has been shown to have various biological effects including disease treatment and prevention. TQ is believed to share similar properties to the benzoquinones already in use as therapeutic drugs. Based on previous reports on the …
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Biochemische Charakterisierung und Wirkoptimierung potentieller Chemotherapeutika auf Basis der natürlichen Chinone Doxorubicin und Thymochinon
… – Bestandteil des Schwarzkümmel-Extraktes (Nigella sativa) – sind aufgrund von antioxidativen und antitumoralen Effekten potentielle Kandidaten zur Weiterentwicklung zum Chemotherapeutikum. Durch die Funktionalisierung von Thymochinon mit verschiedenen gesättigten und ungesättigten bzw. …
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Synthese, Funktionalisierung und Wirkoptimierung natürlicher Chinone
… welches Hauptbestandteil des Schwarzkümmels (Nigella sativa) ist, wurde an verschiedenen Positionen derivatisiert. Es zeigte sich, dass dafür der C-6-Kohlenstoff am besten geeignet ist. Es konnten mithilfe einer Radikalreaktion neben vielen Fettsäurekonjugaten auch TQ-Derivate mit …
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Exploring folate conjugated liposomal delivery of thymoquinone as a novel targeted treatment for human papillomavirus associated cancers
… delivery. Thymoquinone (TQ), a component of Nigella Sativa has been shown to have anti-inflammatory, antioxidant and anticancer properties for different types of cancers. Although it has been shown to induce cell apoptosis for cervical cancer cells in vitro, its anti-HPV effect and the …