Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Nicotine withdrawal"”.
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The Role of MAGL Inhibition in Nicotine Withdrawal and Reward
ROLE OF MAGL INHIBITION IN NICOTINE WITHDRAWAL AND REWARD. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. by Pretal Ishvarlal Patel Muldoon Director: M. Imad Damaj, PhD Professor, Department of …
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Nicotine withdrawal causes transient elevations in brain stimulation reward thresholds
Nicotine withdrawal is associated with dysphoria and depression in humans. In rats, withdrawal from amphetamine, cocaine, or morphine attenuates the motivation to respond for rewarding electrical brain stimulation. It has been proposed that such attenuation of brain stimulation reward reflects …
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NICOTINE WITHDRAWAL AND DEFICITS IN COGNITIVE FLEXIBILITY: POSSIBLE TIES TO ABERRATIONS IN FRONTOSTRIATAL BDNF SIGNALING
Nicotine addiction continues to be a leading cause of preventable death worldwide. Despite the plethora of available treatments for smoking cessation, smoking relapse after attempts to quit remains high. It is possible that impairments in cognitive flexibility and underlying neurochemical circuits …
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The Effects of Transdermal Nicotine on Tobacco/Nicotine Withdrawal and Concurrently Administered Cigarettes in Women and Men
Transdermal nicotine (TN) is a smoking cessation pharmacotherapy thought to work by suppressing tobacco/nicotine withdrawal and reducing the effect of a concurrently smoked tobacco cigarette. Clinical trials suggest that TN may be less efficacious for women. This study explored the possibility of …
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Strain-dependent and age-dependent effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning.
… in both humans and animals demonstrates that nicotine addiction is a complex disorder that can be influenced by several factors. For instance, individual differences in genetics can impact sensitivity to nicotine and can modulate the severity of nicotine withdrawal. Although nicotine alters …
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NICOTINE MODULATION OF THYROID HORMONE SIGNALING AND ITS CONTRIBUTION TO COGNITION
… Thyroid hormones may specifically be affected by nicotine exposure through cigarette smoke. The present work begins with a thorough analysis of the literature on thyroid hormones, their contribution to cognition and synaptic plasticity as well as evidence supporting an interaction between nicotine …
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The Effects of Nicotine on Attention Orienting
… salient stimuli. It is often reported that nicotine can enhance top-down attention control and reduce distraction. In experiments 1 and 2, the effects of increasing control demands on behavior were assessed using electrophysiological (EEG) and behavioral measures in an auditory number parity …
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Caffeine and Nicotine : A Review of Their Combined Use, Interactive Effects and the Impact of Caffeine Abstinence on Tobacco Cessation and Withdrawal
… (caffeine intake increases anxiety/arousal - nicotine decreases it), and combined effects of third variables (e.g., stress, alcohol).</p> <p>In abstinent smokers, caffeine plasma levels increase, remain elevated for as long as six months and may be sufficient to produce a caffeine toxicity …
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Beliefs of mental health nurses about smoking by clients of inpatient mental health facilities
… of smoke-free policies than those who were nicotine dependent. Smoke-free nurses also expressed more concern about the effects of passive smoking on smoke-free staff and clients. Nicotine dependent nurses were more likely to perceive a positive role for smoking in the development of …
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Nicotine Addiction and Impulsive Behaviour: Disentangling the Relationship
… This was achieved by exploring the effects of nicotine in two animal paradigms of impulsivity; the delayed reward paradigm which assessed impulsive choice,and the symmetrically reinforced go/no-go visual discrimination task which measured behavioural disinhibition. A series of preliminary …
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P300 Topographic Differences Between Smokers and Nonsmokers During a Visual Continuous Performance Task
… have been utilized to examine the effects of nicotine and smoklng on brain activity and information processing. These previous results indicate that nicotine decreases P300 latency and increases P300 amplitude, indices which suggest faster and more efficient information processing. Nicotine's …
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Regulation of Expression and Function of Neuronal Nicotinic Receptors by Accessory Subunits
Nicotine binds to nicotinic acetylcholine receptors (nAChRs) and perturbs the biogenesis and trafficking of these channels. The α4β2 and α3β4 subtypes are the most abundantly expressed nAChRs in the central and peripheral nervous system, respectively, and are key mediators of nicotine dependence …
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Behavioral Intervention for Smoking Cessation in Adolescents and Young Adults
… cognitions related to unpleasant events, nicotine withdrawal symptoms, smoking urges and nicotine dependence symptoms. Finally, there were preliminary indications that treatment ameliorated depressive symptoms in individuals with a history of a depressive disorder. Participants rated …
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Premature aging of the lungs of the offspring induced by maternal nicotine exposure during gestation and lactation: protective effects of tomato juice
… The offspring is as a result exposed to nicotine through the blood and the milk of the mother. Nicotine is thus expected to interact with the developing fetus and the offspring of mothers who smoke or use NRT for smoking cessation, resulting in the interference with normal fetal and …
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Improving smoking cessation for vulnerable populations in low-resourced settings
… Aim 1, we examine the association between urine nicotine metabolite ratio (NMR) and response to smoking cessation treatment among people with HIV in South Africa, using data from a large randomized controlled trial for smoking cessation among Black South African smokers with HIV. In the primary …