Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"New Delhi metallo-β-lactamase"”.
-
Discovery and optimization of inhibitors and probes that target New Delhi metallo-[beta]-lactamase
… of β-lactam hydrolyzing enzymes, known as β-lactamases, threatens their clinical efficacy. β-lactamases typically have a conserved serine in their active site that serves as a nucleophile in hydrolysis of the β-lactam substrate. Codrugs in the form of covalent inhibitors that target this …