Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Neutrophil Swarming"”.
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Proposed in vitro model of neutrophil swarming in a chronic, low-level inflammatory state
… and pre-disposes murine models for fatal sepsis. Neutrophils are the most prevalent circulating innate immune cell and their homotypic aggregation, or swarming, is a key mechanism in clearing pathogens greater than 20 μm in size. We hypothesize that neutrophil swarming ability is altered when in a …
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Understanding how neutrophils self-organise their migration to sites of inflammation in vivo
Neutrophils are major effectors of acute inflammation and microbial defence. Their infiltration and migration in injured tissue are critical for the inflammatory response. They are often observed navigating in a highly co-ordinated and directed manner leading to their aggregation at the target site …
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Investigating Pulmonary Immune Responses that Detect and Counteract Gram-negative Bacterial Infections
… coli bacteremia, we observed in vivo pulmonary neutrophil and platelet interactions that resulted in immunothrombosis. Intravital microscopy and novel single cell behavioral analysis revealed that cathelicidin initiated neutrophil swarming and clustering, which preceded LTB4 dependent …
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The Impact of Candida albicans Glycogen on Fitness, Virulence and Host Response
… vaginal colonization concomitant with reduced neutrophil recruitment. Complete inability to catabolize glycogen (gph1∆/∆sga1∆/∆) also rendered C. albicans significantly less virulent during disseminated candidiasis. Using nuclear magnetic resonance (NMR) profiling, we confirmed that …