Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"Neutral lipids"”.
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Fatty acids in neutral lipids and phospholipids from chicken tissues
Thesis (M.S.)--Michigan State University. Dept. of Food Science, 1965
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Structural effects of neutral lipids on the divalent cation-induced interactions of phosphatidylserine - containing bilayers
… the resultant structures might be modified by neutral lipid species. X-ray diffraction data from multilamellar systems suggest that phosphatidylcholine (PC) and diacylglycerol (DG) might be in the collapsed phase up to a concentration of -30 mole % and that above this concentration these …
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Interactions of ferriprotoporphyrin IX with neutral lipids and detergents: insights into their role in β-haematin formation
… detoxifies to form the bio crystal, haemozoin. Neutral lipids have been implicated as the biological molecules responsible for the nucleation of haemozoin in vivo, though their exact role is unclear. This thesis has investigated the interaction between these lipids and Fe(III)PPIX. By exploiting …
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Part I: In-situ fluorometric quantification of microalgal neutral lipids Part II: Thermal degradation behavior of investment casting polymer patterns
… Part-I is focused on in-situ determination of neutral lipid content of microalgae using a lipophilic fluorescent dye. The traditional Nile red stain-based method for detecting microalgal intracellular lipids is limited due to varying composition and thickness of rigid cell walls. In this study, …
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Effect of dietary omega-3 supplementation on plasma phospholipids, neutral lipids fatty acids and antioxidant status of pregnant women with gestational diabetes and their neonates
… level of docosahexaenoic acid (DHA) in phospholipids of maternal and cord red blood cells and cord plasma. This finding was of major concern because DHA is vital for maternal wellbeing and health, and for optimal development of foetal brain and retina. GDM is also associated with increased …
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Investigating the regulation of tumour associated lipogenesis using the model organism, Saccharomyces cerevisiae
… To investigate the role of the HOG1 pathway in neutral lipid accumulation, a Nile red assay was undertaken to measure lipid accumulation in stationary phase of genomic deletion strains of key HOG pathway proteins. Deletion of the majority of HOG components had no effect on lipid accumulation. …
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Elucidating the Role of Yeast Lipin (PAH1) in Lipid Droplet Biogenesis
… of cellular functions including the storage of neutral lipids, but factors that regulate the biogenesis and maintenance of these organelles remain relatively unknown. The primary focus of this dissertation will be to understand the role of the phosphatidic acid hydrolase (Pah1p) in the …
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Phyisiological, genomic and metabolic characterization of the oleaginous yeast Papiliotrema laurentii UFV-1
… yeast Papiliotrema laurentii UFV-1 presented the lipids in the culture media with glucose and xylose as carbon sources. Unlike most oleaginous yeasts, lipid accumulation by P. laurentii UFV-1 begins at the exponential growth phase, presentin a lipid accumulation growth associated. Furthermore, …
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Assessment of wastewater algae for use in biofuel production
… derived from microalgae as they are a carbon neutral source of fuel. The aim of this research was to assess if algae derived from municipal wastewater sources could be potential biofuel feedstocks by assessing their growth and fatty acid accumulation. When comparing wastewater derived algae to …
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The relationship between docohexanoic acid (DHA) and L-serine, providing an insight into the biochemistry of meningioma
… was altered. Once synthesised, these neutral lipids go on to be 4 stored in membrane bound organelles. Within the phenotype of cancerous cells, such storage of neutral lipids into lipid droplets prevent lipotoxicity. The light microscopy study of L. starkeyi cells supplemented with …
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Supercritical Fluid Extraction and Chromatography of Various Lipids from Soybean Lecithin
Phospholipids are commonly found in biological membranes. They have a polar head group and two ester linked fatty acids tails. Different methods such as thin layer chromatography and high performance liquid chromatography coupled with ultraviolet, refractive index, flame ionization detector, and …
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Improving biomass of the marine microalga Nannochloropsis oculata by chemical elicitation
… such as antioxidant and antimicrobial potential. Neutral lipids produced by microalgae are also of huge importance because of their desirable characteristics for the development of new generation biofuels. Stress culture conditions, such as nitrogen starvation, are favourable for inducing the …
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A dielectrophoretic, microfluidic device for sorting lipid-producing organisms used as bio-oil sources
… algae, and bacteria produce high fractions of neutral lipids as part of normal metabolism, and are being explored as a hydrocarbon source for products such as biodiesel, nutraceuticals, and more. Thus, there is a global effort to select or genetically engineer microorganisms that produce higher …
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Investigating the Effects of Sodium Benzoate on Fat Deposition, Pharyngeal Pumping, and Related Genetic Mechanisms in Caenorhabditis elegans
… of Oil Red O, implement chemical analysis of lipids through gas chromatography-mass spectrometry to inspect true staining of neutral lipids or lipofuscins, and measuring C. elegans life span to assess sodium benzoates of either being an obesogenic chemical or inducer of oxidative stress.
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The Role of Transmembrane Domain Helix-Helix Interactions in the Function of Pentameric Ligand-Gated Ion Channels
… in membranes lacking activating anionic and neutral lipids. The lipid-exposed transmembrane alpha-helix, M4, in each homologous subunit likely acts as a lipid sensor. One model proposes that activating lipids promote M4 “binding” to the adjacent alpha-helices, M1 and M3, to enhance …
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Lipid Production from a Louisiana Native Chlorella vulgaris/Leptolyngbya sp. Co-culture for Biofuel Applications
… nitrate nitrogen levels on total lipid yield, neutral lipid portion, and fatty acid profile of non-aerated and aerated co-cultures were investigated in bench top scale experiments. The maximum lipid productivities were ~17 and 116 mg L-1d-1 for non-aerated and aerated cultures respectively. The …
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The Role of Mammalian Lipid Transport Protein ORP1 During Coxiella Burnetii Infection
… the CCV to the ER, as lipid droplets form from neutral lipids in the ER. While the absence of ORP1 led to a C. burnetii growth defect in MH-S cells, there was no growth defect in HeLa cells. Together, our data demonstrate that C. burnetii uses the host sterol transport protein ORP1 to promote …
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The study of spherical high-density lipoproteins and the intermediates involved in their formation
… particles in the circulation, contain a core of neutral lipids, mainly cholesterol esters and an outer shell of apolipoproteins, phospholipids, and cholesterol. Discoidal HDL, discovered in the plasma of patients deficient in lecithin cholesterol acyltransferase (LCAT), become spherical in …
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Protein quality control in the mammalian endoplasmic reticulum
… droplets are cytoplasmic organelles that store neutral lipids. Based on the data that AUPI depletion affects both ER quality control and lipid droplet formation and that pharmacological inhibition of lipid droplet formation perturbs dislocation, we propose that lipid droplet formation may also …
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Proteome-wide Functional Profiling of Serine Hydrolases in the Human Malaria Parasite
… of ester bonds of lipid species such as neutral lipids and phospholipids. Although roles of lipases in propagation, as well as virulence in various organisms, have been acknowledged, in P. falciparum lipases remain understudied. We combined LC-MS/MS with the SH-directed ABPP to identify …
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