Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"Neurovascular dysfunction"”.
-
Neuronal and Vascular Degeneration of the aging retina in the 3xTg-AD mouse
… deposition in the central nervous system (CNS), neurovascular dysfunction, and neuroinflammation. Diagnostic modalities to detect the early phases of these CNS pathologies in preclinical AD are inadequate. Vision abnormalities are common in AD, and Aβ and tau have been detected in the retina …
-
Molecular characterisation of the role of systemic infections in Alzheimer’s disease brain
… and tau pathology, glial activation, vascular dysfunction, and systemic influences. This thesis investigates how systemic infection reshapes the molecular architecture of the AD brain and introduces Genedex, a framework to contextualise transcriptional findings within the broader AD continuum. …