Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"Neurorestorative"”.
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Drp1 inhibition is protective against mitochondrial and autophagic impairment induced by alpha-synuclein
… with currently no effective neuroprotective or neurorestorative treatments available. Alpha-synuclein (α-syn) pathology is one of the key proteins involved in PD pathology, it has been found to induce mitochondrial dysfunction, yet the mechanism is not entirely understood. This thesis project …
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Neuroprotective effects of incretin mimetics upon chronic endoplasmic reticulum (ER) stress : implications for novel therapeutic pathways and opportunities in Alzheimer's disease
… that incretin mimetics exert neuroprotective and neurorestorative effects across a range of experimental models of neuronal degeneration. In a recent pilot clinical trial, Liraglutide rescued the decline of the cerebral glucose consumption in Alzheimer’s disease (AD) patients, signifying improved …
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The role of the dopaminergic neurotrophin growth/differentiation factor-5 in the developing rat ventral midbrain
… has also been shown to have neuroprotective and neurorestorative effects on adult dopaminergic neurons in the substantia nigra in animal models of Parkinson’s disease (Sullivan et al. 1997, 1999; Hurley et al. 2004). This experimental evidence has lead to GDF-5 being proposed as a neurotrophic …
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The clinical utility of multidisciplinary rehabilitation in individuals with Huntington’s Disease
… findings, particularly with respect to the neurorestorative properties of multidisciplinary rehabilitation.