Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Neuroprotective Potential"”.
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Neuroprotective Potential of a Lanosteryl Triterpene from Protorhus longifolia Stem Bark (Benrh.) Engl in high fat diet fed and STZ -induced diabetic neuropathy in rats
… exploration of natural products as alternative potential remedies for the disease treatment. The present study aimed at investigating the neuroprotective potential of lanosteryl triterpene (RA-3) from Protorhus longifolia stem bark in high fat diet (HFD) fed and streptozotocin (STZ) -induced …
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Neuroprotective Effects of Anthocyanins on Neuronal Death Induced by Inhibition of Bcl-2 and Oxidative Stress
… to neuronal death. Here, we investigated the neuroprotective effects of a novel class of nutraceuticals, anthocyanins, against MOS-induced death in primary cultures of rat cerebellar granule neurons (CGNs). Anthocyanins are natural antioxidants whose neuroprotective potential has yet to be …
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Defining the potential of HDAC5 and HDAC9 as therapeutic targets for Parkinson’s disease
… pathological hallmark of PD. Identification of neuroprotective and disease altering factors are essential for the development of new therapies. The targeted inhibition of histone deacetylases (HDACs), enzymes which regulate histone acetylation, have shown some promise in this regard. For …
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Adapt, Survive or Die - Metabolic Imbalances and the Enteric Nervous System
… Both GLPs are reduced in ODC. We showed a great neuroprotective potential of the hormones. Based on these findings, HFD-induced enteric neuronal loss is suggested to be a culmination of several factors, including increased PA- and LPS-exposures and a decreased GLP level, leading to dysregulation …
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THE PROPHYLACTIC POTENTIAL OF DOCOSAHEXAENOIC ACID, AN OMEGA-3 FATTY ACID, IN TRAUMATIC BRAIN INJURY
… (ω3 FAs), known for their anti-inflammatory and neuroprotective benefits, are highly accessible in both dietary and supplementary sources. However, the information surrounding the effect of ω3 FA supplementation on the brain in response to TBI is highly inconsistent and not well understood. This …
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Protein Misfolding and Aggregation in Neurodegeneration: In Vitro And In Vivo Study Cases
… 11 aa of human HK1 and tested its action as a potential interfering molecule between VDAC1/SOD1-G93A bond. Both in a protein-protein interaction and in a protein mitochondrial interaction we obtained a decrease of VDAC1/SOD1-G93A binding with respect of the increased N-HK1 peptide …
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The potential application of rapeseed pomace extracts in the prevention and treatment of neurodegenerative diseases.
… In an attempt to revalorize this by-product as a potential nutraceutical for the treatment or prevention of neurodegenerative disease, this project aimed to determine (i) a suitable extraction technique, (ii) the phytochemical composition and in vitro activity of the extract, in relation to …