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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 122 for “"Neurone"”.

  1. Redoxmodulation Hippokampaler Neurone

    Gerich, Florian2012

    … auf Einzelzellebene (in kultivierten Neuronen) und auf molekularer Ebene durchgeführt. Extrazellulär appliziertes H2O2 (200 µM) führte zu einem Anstieg von [Ca2+]i, offensichtlich durch Freisetzung aus RyR-sensitiven intrazellulären Speichern. Das mitochondriale Membranpotential, die …

    goettingen Repository record

  2. Engaging with Motor Neurone Disease

    King, GabrielleThe University of Edinburgh2021

    … research engagements in the context of Motor Neurone Disease (MND). To do this, I use interviews and observations to explore how experiences are shaped and situated. By connecting geography, science studies, disability and applied health research, the project brings together debates around …

    edinburgh Repository record

  3. Analyse Neurone-generierender Zellteilungen im Neuroepithel der Maus

    Haubensak, Wulf EckhardUniversität Heidelberg

    … Neuroepithel (Neuroepithelzellen) und damit die Neuronenzahl des Gehirns vermutlich durch den Übergang von im cell fate symmetrischen, proliferativen (Generierung zweier Neuroepithelzellen) zu asymmetrischen differenzierenden Zellteilungen (Generierung einer Neuroepithelzelle und eines Neurons) …

    heid-diss Repository record

  4. Outcomes of Enteral Feeding in Motor Neurone Disease

    Chhetri, Suresh KumarUniversity of Central Lancashire2015

    Motor Neurone Disease (MND) is a fatal neurodegenerative disease of unknown aetiology characterised by the degeneration of motor neurones leading to progressive wasting and weakness of the bulbar, limb and respiratory muscles. Symptomatic treatment remains the cornerstone of management. …

    cent-lancashire Repository record

  5. Untersuchung zur Proliferation neocorticaler und hippokampaler Neurone in vitro

    Thyerlei, Dinah

    … Proliferation neocorticaler und hippokampaler Neurone in vitro. Ziel war, neocorticale Primärkulturen der neugeborenen Ratte nach Zelltypen aufzutrennen und in reineren Kulturen zu vermehren. Besonderes Interesse galt der Anreicherung neuronaler Präkursoren und der Kultur reiner Astrozyten. …

    freiburg-diss Repository record

  6. Understanding mechanisms related to psychosis in Motor Neurone Disease

    Wilcox, AliciaUniversity of Cambridge2020

    … a challenging feature of the syndromes of motor neurone disease (MND), frontotemporal dementia (FTD) and their overlap (FTD-MND). Clinically evident psychosis is not common, except in those with C9orf72+ expansions. However, subthreshold psychosis or pre-psychosis processes are common and provide …

    cambridge Repository record

  7. Motor neurone and muscle nuclear changes in development and disease

    Vassilopoulos, D.The University of Edinburgh1976

    … unclear. It was felt that a study of the motor neurone and muscle nucleus in development and disease might reveal the extent of its participation in some of these disease processes. 1. A quantitative histochemical and histometric study of the developing anterior horn cell nucleus during fetal …

    edinburgh Repository record

  8. Role of eEF1A-2 in the pathogenesis of Motor Neurone Disease

    Newbery, HelenThe University of Edinburgh2003

    Motor neuron disease, or amyotrophic lateral sclerosis (ALS), is a disorder characterised by progressive weakness and atrophy of skeletal muscles, caused by the selective loss of motor neurons. It occurs in both familial and sporadic forms. Although the genetic basis of the disease in a minority of …

    edinburgh Repository record

  9. Wirkung von Johanniskrautextrakt im Vergleich zu Fluoxetin auf sich entwickelnde Neurone in vitro

    Kehrle, FeliciaUniversität Ulm

    ulm-diss Repository record

  10. The involvement of free radicals in the casual mechanism of Motor Neurone Disease

    Fitzmaurice, P.S.University of Central Lancashire1996

    … cell viability. The progressive loss of motor neurones associated with motor neurone disease (MND) may be due to acute or chronic free radical damage causing irreversible cell lesions. Perturbation in the mechanisms involved in the cell's protection against the deleterious effects of free …

    cent-lancashire Repository record

  11. Mutazione LRRK2-G2019S all'interfaccia dell'interazione astrocita- neurone durante lo sviluppo post natale e l'invecchiamento

    GIACHINO, CARMELAUniversità degli studi di Catania2022

    … sviluppo postnatale delle interazioni astrocita-neurone e durante il processo di invecchiamento. Utilizzando colture primarie derivate dal mesencefalo di topi WT-LRRK2 e TG-G2019S, abbiamo identificato un ruolo inibitorio chiave degli astrociti LRRK2 G2019S nella crescita e differenziamento dei …

    catania Repository record

  12. The personal experience of carers of individuals with Motor Neurone Disease (MND) and their experiences of services

    Smith, Hayley-JaneUniversity of Birmingham2009

    … individuals with a partners diagnosed with Motor Neurone Disease (MND). Lastly, a public domain provides a summary of the empirical paper.

    birmingham Repository record

  13. A review of cases of motor neurone disease seen at Groote Schuur Hospital from 2005 to 2010

    Daude, AminaDepartment of Medicine2014

    Motor neurone disease (MND) is a rare progressive neurodegenerative disorder in which selective degeneration of the motor neurones of the brain and spinal cord occurs. Progressive weakness of limb, bulbar and respiratory muscles eventually results in death. Most descriptive and epidemiological …

    cape-town Repository record

  14. Population-based genotype-phenotype correlation to stratify incident cases of motor neurone disease in Scotland from 2015-2017

    Leighton, Danielle JaneThe University of Edinburgh2020

    BACKGROUND: Motor neurone disease (MND) refers to a spectrum of rapidly progressive neurodegenerative diseases for which there remains no cure. A recognised and crucial barrier to more accurate diagnosis, prognosis and treatment relates to phenotypic heterogeneity. Recent discoveries in the genetic …

    edinburgh Repository record

  15. Development and analysis of hierarchical feedforward neural network systems for classification of motor neurone disease based on magnetic resonance spectra

    Refaee, MohamedUniversity of Central Lancashire2001

    … in brain metabolites are associated with Motor Neurone Disease (MND). Magnetic Resonance Spectroscopy (MRS) has been performed on the brains of MND patients and control volunteers to acquire signals which contain information about brain metabolites from within the motor cortex area. …

    cent-lancashire Repository record

  16. A qualitative study into the communication surrounding the initiation and withdrawal of non-invasive ventilation (NIV) in people with Motor Neurone Disease

    Chapman, CharlotteEdith Cowan University, Research Online, Perth, Western Australia2019

    Introduction Motor neurone disease (MND) is a degenerative disease that adversely affects the nervous system and muscular control. Eventually respiratory muscles weaken, causing breathing, communication and swallowing difficulties, and ultimately, respiratory failure and death. Improved quality of …

    edithcowan Repository record

  17. Auswirkungen der Überexpression von neuronalem p21ras auf cholinerge Septumneurone der Maus : eine stereologische Studie

    Ziller, Matthias Georg

    … cholinerger septohippokamplar Projektionsneurone von Nervenwachstumsfaktor (NGF) abhängig. Über die intrazelluläre Vermittlung dieses Effektes ist wenig bekannt. p21ras ist ein Schlüsselmolekül in der Signaltransduktion von NGF. Um dessen Funktion in cholinergen Neuronen in vivo zu …

    freiburg-diss Repository record

  18. Antwortverhalten Galanin-immunoreaktiver isolierter Spinalganglienzellen der Ratte auf Hitze- und Capsaicinstimulation in Abhängigkeit von neurotrophen Faktoren

    Engert, SabineUniversität Würzburg

    … dass es Galanin-immunoreaktive sensorische Neurone in der Ratte gibt, die gleichzeitig Hitze-sensitiv sind. Hierfür wurden Spinalganglienneurone der Ratte bis zu 6 d in Medium ohne NGF kultiviert. Mit Hilfe einer Doppelfärbung, bestehend aus Hitze- bzw. Capsaicin-induzierter Cobalt-Aufnahme …

    wurz-thes Repository record

  19. Über den Zusammenhang von Galaninexpression und Capsaicinempfindlichkeit in Spinalganglionneuronen von Ratten mit experimentellen Nervenverletzungen

    Wendland, Jens RobertUniversität Würzburg

    … der Galaninexpression in einzelnen Spinalganglionneuronen unter verschiedenen Bedingungen untersucht. Diese Eigenschaften wurden gewählt, weil beide nach experimentellen Nervenverletzungen starken Veränderungen unterliegen und weil beide über „nerve growth factor“ reguliert werden. Neurone von …

    wurz-thes Repository record

  20. Candidate mechanosensitive transduction channels in Drosophila melanogaster

    Effertz, Thomas2012

    … und besteht aus ca. 500 mechanosensorischen Neuronen. Diese JO-Neuronen wandeln stimulus induzierte Antennenbewegungen in neuronale Signale um und verstärken darüber hinaus die induzierten Bewegungen und somit das eigentlich Eingangssignal. Vorhergehende Arbeiten konnten zeigen, dass die …

    goettingen Repository record

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