Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Neuronal regulation"”.
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Neuronal Regulation of the Innate Immune Response in Caenorhabditis elegans
… the role of dopamine signaling and underlying neuronal circuits in regulating the C. elegans innate immune response.</p><p>Through genetic and pharmacological studies, we identified a D1-like dopamine receptor, DOP-4, which suppresses the conserved PMK-1/p38 immune pathway in C. elegans. We …
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Neuronal regulation of haematopoietic stem cell ageing and age-related blood disorders through the microenvironment
… with a particular focus on microenvironmental regulation of myelopoiesis/megakaryopoiesis in response to neuronal inputs. During normal ageing, HSC niches decrease near bone but expand further from bone. Adrenergic signalling regulates lymphoid-myeloid balance during ageing. Whereas β2-AR …
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The Roles of daf-6 and Cell-Cell Interactions in Sensory Organ Morphogenesis
… of multicellular organs depends on the regulation of cell shape, position, and orientation. The genetic regulation of these morphogenetic processes is poorly understood. As a model for organ morphogenesis, I studied the development of the Caenorhabditis elegans amphid sensory organ. …
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The Diversity of FHF-mediated Ion Channel Regulation
… regulating channel activity and consequently neuronal excitability. Mutations in FGF14 cause spinocerebellar ataxia while FGF13 is a candidate for X-linked mental retardation. Since FGF13 and FGF14 are nearly identical within their respective VGSC-interacting domains, those distinct …
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Characterization Of Neuronal Groups Regulating Sexual And Agonistic Behavior In Male Chicken (Gallus Gallus)
<p>The study aimed to understand the neuronal regulation of male sexual and agonistic behavior in broiler breeders. First, brain structures associated with sexual and agonistic behavior were identified by mapping Fos expression. The ventromedial subnucleus of medial portion of bed nucleus of the …
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Investigation of enteric neuron and type 2 lymphocyte interactions at homeostasis and during Nippostrongylus brasiliensis infection
… interactions between ILC2s and distinct enteric neuronal populations not yet explored. In this thesis, a population of murine enteric neurons was identified as a meaningful player in the regulation of type 2 lymphocyte responses in steady-state conditions and after infection with *Nippostrongylus …
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Amino acid transmitters and the neural control of feeding and energy homeostasis
… strides have been made in understanding the neuronal regulation of energy balance, there is a need to more fully understand the homeostatic systems within the hypothalamus that are so powerful that they are able to drive individuals to poor health or death, often even in the face of …
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Cholinergic signals promote the quiescence of normal or leukaemic stem cells through the activation of the α7-nicotinic receptor in bone marrow mesenchymal stromal cells
The sympathetic nervous system has evolved to respond to stress and activates haematopoietic stem cells (HSCs) using noradrenergic signals. However, the pathways that maintain HSC quiescence and maintenance during proliferative stress are not well understood. This study has investigated the role of …