Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 56 for “"Neuronal circuits"”.
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Control of neuronal circuits: from biology to robotics
… retain some of the desirable properties of neuronal circuits, but lack the physical embodiment that is characteristic of biological systems and that is key to their effectiveness. In this thesis we take a step towards reconciling biophysics with bio-inspired control, using the language of …
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Engineering novel neuronal circuits using HI-PSCS derived neurons and microglia
… during the development and refinement of the neuronal circuits in the brain. From previous in vivo studies, we know that microglia mediate the synaptic pruning during neuronal circuit formation, and thus we hypothesized that microglia will remodel the connections within the human cortical …
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Characterization of the neuronal circuits and peptides underlying behavior in nudipleuran sea slugs and Octopus rubescens
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Characterization of the neuronal circuits and peptides underlying behavior in nudipleuran sea slugs and Octopus rubescens
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Control of Neuronal Circuit Assembly by Gtpase Regulators
… which is crucial for the functioning of neuronal circuits. Thus, understanding the cellular and molecular mechanisms leading to the precise assembly of neuronal circuits is a major focus of developmental neurobiology. The structural organization and specific connectivity of neuronal …
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Μελέτη της συναπτογενέσεως του ακουστικού φλοιού in vitro άνευ και κατόπιν ηλεκτρικού ερεθισμού ανάλογου προς τα ηλεκτρικά δυναμικά ενέργειας του κοχλιακού νεύρου
The synaptogenesis and the neuronal interactions of the rat's acoustic cortex were studied in explants cultured in vitro, exposed to a continuous sound of a certain frequency. The morphological findings were correlated morphologically with explants of the same area of the cortex from the same …
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Regulation of mammalian neuronal circuit development by CPG 15
The orderly assembly of neuronal circuits is specified by developmental programs of gene expression, however, the final stage in circuit development, maturation and refinement of specific synaptic connections, is strongly influenced by neuronal activity. It is thus not surprising that the products …
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Connectome and Ultrastructural Studies of an Anthozoan Planula: Exaiptasia diaphana
… is known about their origin and how the first neuronal circuits functioned. The sea anemone Exaiptasia diaphana, a cnidarian and sister group to all bilaterians, holds a key position for comparative studies. Alongside ctenophores, cnidarians are the only non-bilaterian phyla with a nervous …
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The Impact of Gamma Stimulation on Neurological Phenotypes of Alzheimer's Dementia and Down Syndrome
… frequency activity in hippocampal and cortical neuronal circuits and improving cognitive performance in the setting of AD and DS.
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Neuronal Regulation of the Innate Immune Response in Caenorhabditis elegans
… the role of dopamine signaling and underlying neuronal circuits in regulating the C. elegans innate immune response.</p><p>Through genetic and pharmacological studies, we identified a D1-like dopamine receptor, DOP-4, which suppresses the conserved PMK-1/p38 immune pathway in C. elegans. We …
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Network coherence in autism spectrum disorder : a multimodal neuroimaging study of functional connectivity and spectroscopy MRI
The underlying neuropathology and effects on neuronal activity in individuals with ASD are still being elucidated; as well as their impact on intervention and treatment outcomes. Frontal, temporal, parietal and cerebellar pathways exhibit disrupted structural and functional connectivity in …
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Electrochemical and Magnetochemical Approaches for Neuronal Modulation
… of unstable chemical signals to targeted neuronal circuits with nanoscale electrocatalysts, biocompatible precursors, and electric fields. This electrochemical system is implemented in an implantable probe allowing for the investigation of neurophysiological processes mediated by unstable …
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Neuromast Optogenetics Reveals Rules of Spatial Encoding in the Zebrafish Lateral Line
… effectively to their environment, their sensory circuits must learn to distinguish between similar patterns of sensory information. A lingering question in neuroscience is how neuronal circuits achieve this performance. In this study, I use the posterior lateral line (pLL) of larval zebrafish to …
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Deficient experience-dependent plasticity in the visual cortex of Arc null mice
… molecules work in concert to sharpen and refine neuronal circuits throughout development. With the advent of genetic mouse models it is now possible to probe the individual contributions of single molecules implicated in this process. The Arc (activity-regulated cytoskeletal associated) gene is …
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EGFR signaling regulates synaptic connectivity via Gurken
… is critical for establishing functional neuronal circuits. The mechanisms regulating target selection remain incompletely understood. I describe a role for the EGF receptor and its ligand Gurken in target selection of octopaminergic Type II neurons in the Drosophila neuromuscular system. …
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Spatially restricted proteomic mapping of excitatory and inhibitory post-synaptic termini through enzymatic labeling
The neuronal synapse is the seat of cognitive computation in the brain, where the minor adjustments in electrical activity between various neuronal circuits results from the sophisticated orchestration of molecules at the synapse. The molecular interplay between the diverse range of synapses and …
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Cellular signalling pathways involved in thermoprotection of neural ciruit function in the locust.
… extend the thermal operating range of neural circuits during exposure to extreme heat. It is unclear how HS preconditioning confers CNS thermotolerance. I used the migratory locust (Locusta migratoria), an animal that inhabits environments that can have large fluctuations in ambient …
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Visual navigation of a virtual blowfly
… eye, as an important source of information. The neuronal circuits analysing these image movements in the brain of blowflies are well known. This thesis presents a detailed algorithmic model for this neuronal module of the fly and shows that this model is capable of quantitatively reproducing the …
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Neural Activity Within and Between Visual and Executive Areas Is Modulated Post-Locomotion in Rhesus Macaques
… of physical activity, such as locomotion, on the neuronal circuits underlying cognitive processes have yet to be fully characterized. This body of work seeks to rectify this gap in knowledge through analysis of how both behavioral performance and neuronal activity signatures in visual and …
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Feature Topography and Sound Intensity Level Encoding in Primary Auditory Cortex
… how sounds are represented and transformed by neuronal circuits in this area. The topographic organization of neuronal responses to auditory features in A1 provides evidence for potential mechanisms and functional roles of this neural circuitry. This dissertation presents results from models of …
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