Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Neuronal Phenotype"”.
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Induction and Inhibition of a Neuronal Phenotype in Spodoptera Frugiperda (Sf21) Insect Cells
… the growth medium, Sf21 cells began to express neuronal morphology, or the production of elongated, axon-like processes within 2-3 days. Maximal differentiation occurred when in the presence of 42 μM 20-HE or 10 μM insulin. Effects were maximal on day 2 for 20-E and day 3 for insulin. Insulin …
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Molecular recognition of chlorine-doped polypyrrole
… has been modified to facilitate binding of neuronal phenotype cells. The selection of peptides using phage display found a surface specific recognition peptide (T59) that was made bivalent by altering the C-terminus with an integrin binding epitope. The bivalency of the modified T59 peptide …
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Regulation of n-3 PUFA biosynthesis in proliferating and differentiated PC12 pheochromocytoma cells
… may constitute an important feature of neuronal phenotype acquisition.
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Neuroinflammatory consequences of rhinovirus infection in the human airway
… airway epithelium. <br/><br/>A human sensory neuronal model was derived from differentiation of human dental pulp stem cells towards a neuronal phenotype, termed peripheral neuronal equivalents (PNEs). PNEs were infected for 2, 6, 24, 48 and 72 hrs with major group RV-A16, or minor group …
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ATP, TRP channels and airway neuronal sensitisation
… cells (PBECS) and an in-Vitro human sensory neuronal model differentiated from human dental pulp stem cells termed peripheral neuronal equivalents (PNEs). TRP channels are thought to play a role in the neuronal hyperresponsiveness responsible for chronic cough. Little is know regarding the …
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The PI3-Kinase/TSC Pathway: A Role in Neural and Renal Development and Pathology
… These mice develop macrocephaly accompanied by neuronal hypertrophy and loss of neuronal polarity. The mutant mice also exhibit behavioral abnormalities reminiscent of certain features of human autism. Biochemical analysis indicates that multiple AKT downstream pathways including the TSC/mTOR …
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Functional contributions of a sex-specific population of myelinated aortic baroreceptors in rat and their changes following ovariectomy
… a distinct myelinated baroreceptor (BR) neuronal phenotype termed Ah-type, which exhibits functional dynamics and ionic currents that are a mix of those observed in barosensory afferents functionally identified as myelinated A-type or unmyelinated C-type. Interestingly, Ah-type afferents …
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Processing of Alzheimer's amyloid precursor protein in cultured cells.
… acid induces these cells to differentiate into a neuronal phenotype (NT2N cells), which has been shown to closely resemble immature human CNS neurones. Both cell types produce high levels of endogenous APP.Intracellular and secreted APP was studied in both cell types by means of western blotting …
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Intracellular signaling cascades in the dopaminergic specification of fetal mesencephalic neural progenitor cells.
… of mouse fetal NPCs towards the dopaminergic phenotype and to compare short and long-term expanded NPCs. Long-term expanded fetal mesencephalic NPCs could be grown under suspension and adherent culture conditions and showed self- renewing capacity as well as markers typical for NPCs. They …
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Effects of environmental complexity on neurogenesis in the hippocampal dentate gyrus
… quantify the new born and surviving cells. The phenotype of the surviving cells was examined by means of confocal microscopy and immunofluorescent double-labeling for BrdU and either a marker of neurons (NeuN) or a marker of astrocytes (GFAP). Apoptotic cell death was examined with the TUNEL …
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HIV-1 INFECTION OF NEURAL STEM CELLS RESULTS IN COGNITIVE DEFICITS THROUGH ADULT NEUROGENIC MODULATION
… lineage differentiation, and late-stage neuronal maturation. We performed a series of in vitro and in vivo studies using the HIV-1 Tg26 transgenic mouse model, which mimics HIV-1 patients suffering from low-level and chronic stress from HIV-1 viral proteins in the ART era. NSC culture …