Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 70 for “"Neuronal Network"”.
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Neuronal Network Oscillations in the Control of Human Movement
… a process of disengagement from the existing network to enable the creation of functional assemblies required for movement. Importantly, I also demonstrate a novel neural signature of transient alpha synchrony, that occurs after preparatory desynchronisation, that underlies the recruitment of …
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Using machine learning for analysis of neuronal network activity
Analyzing neuronal activity in developing neuronal networks can improve our understanding of neuronal dysfunctions underlying conditions such as Rett syndrome. Two-photon calcium imaging is used to capture neuronal network activity over time. This method produces large sets of images that are …
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Modeling projection neuron and neuromodulatory effects on a rhythmic neuronal network
… neurons shape the activity of many neural networks. In particular, neuromodulatory substances, which are often released by projection neurons, alter the cellular and/or synaptic properties within a target network. However, neural networks in turn influence projection neuron input via …
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Investigations of neuronal network responses to electrical stimulation in murine spinal cultures.
Spontaneous activity in neuronal networks in vitro is common and has been well documented. However, alteration of spontaneous activity in such networks via conditioning electrical stimulation has received much less experimental attention. Two different patterns of electrical stimulation were used …
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Molecular Substrates And Neuronal Network Subserving Audiogenic Kindling In Genetically Epilepsy-Prone Rats
… Several lines of evidence indicate that the neuronal network of AGS is primarily localized in the brainstem in GEPR-9s. The audiogenic seizure kindling (AGS kindling) process involves periodically repeated induction of AGS. In GEPR-9s induction of 14 or more AGS over 1-2 week period leads to …
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Two-photon calcium imaging sequence Analysis Pipeline : a method for analyzing neuronal network activity
Investigating the development of neuronal networks can help us to identify new therapies and treatments for conditions that affect the brain, such as autism and Alzheimer's disease. Two-photon calcium imaging has been a powerful tool for the investigation of the development of neuronal networks. …
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Neuronal Network Analyses in vitro of Acute Individual and Combined Responses to Fluoxetine and Ethanol
Embryonic murine neuronal networks cultured on microelectrode arrays were used to quantify acute electrophysiological effects of fluoxetine and ethanol. Spontaneously active frontal cortex cultures showed highly repeatable, dose-dependent sensitivities to both compounds. Cultures began to respond …
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Investigating neuronal network dynamics : scale-invariance, preferred firing rates, and plasticity via phase-shift encoding
Understanding how neuronal networks process information and adapt to external stimuli is critical for advancing our knowledge of neural plasticity and computation. Scale-invariant properties, which suggest self-organised criticality (SOC), have been observed in these networks, but the mechanisms …
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NEUROACTIVE AGENTS-MEDIATED CHANGES IN NEURONAL NETWORK ACTIVITY CONTROLS SUSCEPTIBILITY TO SUDDEN UNEXPECTED DEATH IN EPILEPSY (SUDEP)
… (S-IRA) in DBA/1 mouse model of SUDEP, but the neuronal networks mediating S-IRA and the brain structures involved in the fluoxetine-mediated blockade of S-IRA are not known. Data from human SUDEP imaging has underlined the role of periaqueductal gray (PAG), which is also implicated in …
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The role of the periaqueductal gray in modulation of acute and chronic pain: Actions of drugs with analgesic properties on periaqueductal gray neuronal network
… The PAG is a critical nucleus in these pain networks and receives and sends extensive projections within these networks. Chronic pain is a major side effect in 30-70% of cancer patients receiving chemotherapeutic regimen. Endocannabinoids, such as anandamide (AEA), are lipid neuromodulators …
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Effect of space conditions on neuronal plasticity and connectivity
… their specific and combined effects on in vitro neuronal network models. In vitro primary neuronal network cultures were established and exposed to simulated space conditions to investigate neuronal network remodelling (plasticity and connectivity) as well as genomic damage/repair dynamics. This …
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Quantitative phase imaging: advances to 3D imaging and applications to neuroscience
… by studying the emergent formation of a neuronal network. Second, an expansion of this QPI method into a 3D quantitative imaging method, called white-light diffraction tomography (WDT), has been shown. Lastly, an initial result for another advance in SLIM is introduced by combining SLIM …
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Heterogenous Change in Neuronal Bursts Following Recovery from Activity Silencing
Silencing of activity in hippocampal neuronal cultures was used to study how dynamic neuronal activity achieves a state of homeostasis, using calcium imaging to detect neuronal firing patterns. Recovering cultures were found to display abnormal activity patterns after 48hrs of exposure to …
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Dynamics of a fully stochastic discretized neuronal model with excitatory and inhibitory neurons
… extension and generalization of the stochastic neuronal network model developed by DeVille et al.; their model corresponded to an all-to-all network of discretized integrate-and-fire excitatory neurons where synapses are failure-prone. It was shown that this model exhibits different metastable …
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Avalanches in disordered systems
… different sys- tems. The first system is the neuronal network in in vitro rat cortex; neurons generate electrical impulses that travel along axons and dendrites to potentiall influence the behavior of other neurons. The second sys- tem is the deformation characteristics of nanoscale metallic …
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Assessing Neuronal Synchrony and Brain Function Through Local Field Potential and Spike Analysis
<p>Studies of neuronal network oscillations and rhythmic neuronal synchronization have led to a number of important insights in recent years, giving us a better understanding of the temporal organization of neuronal activity related to essential brain functions like sensory processing and …
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Phase-locking of neurons in the hippocampus and the medial prefrontal cortex of the rat to the hippocampal theta rhythm
… formation, yet their basic organization at the neuronal network level is not well understood. Here we investigate the timing relationships between neuronal activity in the medial prefrontal cortex of freely behaving rats and the hippocampal theta rhythm. We demonstrate that a significant portion …
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A Deep Learning Pipeline for Classifying Different Stages of Alzheimer's Disease from fMRI Data.
… for researchers. In this thesis, convolutional neuronal network architecture AlexNet was applied to fMRI datasets to classify different stages of the disease. We classified five different stages of Alzheimer’s using a deep learning algorithm. The method successfully classified normal healthy …
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Neuronal Polarization and Axonal mRNA Localization on Microfabricated Substrates
… approach to study the mechanisms that regulate neuronal behavior, both in small networks and at the subcellular level. The first half of this report shows that high-resolution protein patterns and cellular positioning systems may eventually be used to develop simple, reliable neuronal networks. …
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Neuropeptidomics Across Metazoan Life
… the formation, function and plasticity of neuronal networks, while the honey bee (Apis mellifera) is important for uncovering the mechanisms and evolution of social behavior. As studies in these model organisms are undertaken, knowledge of the complement of neuropeptides used by and …
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