Global ETD Search
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Showing 1 to 14 of 14 for “"Neuromuscular transmission"”.
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Neuromuscular Transmission in the Cockroach, Periplaneta Americana (L)
Made available in DSpace on 2014-12-05T22:14:32Z (GMT). No. of bitstreams: 1 0006025.pdf: 3416306 bytes, checksum: 53446f565b29fc020216483570e47381 (MD5) Previous issue date: 1953
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The Effect of Anticholinesterase Action on Mammalian Skeletal Neuromuscular Transmission
A brief outline of skeletal neuromuscular transmission as a sequence of events leading to muscular contraction and the actions of anticholinesterases is presented in the Introduction. The work has been largely concerned with the irreversible inhibition of cholinesterase by ecothiopate (phospholine) …
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Effects of high hydrostatic pressure on neuromuscular transmission in shallow-living and deep-living crustaceans
… of high hydrostatic pressure on excitatory neuromuscular transmission in shallow- and deep-living crustaceans were compared. Pressure caused depression of the amplitude of excitatory junctional potentials (e.j.p.s) at the neuromuscular junction in the shallow-living crab, Libinia emarginata. …
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Magnesium recurarisation differences between no reversal, neostigmine/glycopyrrolate reversal and sugammadex reversal of neuromuscular block in an in vivo rat model
The neuromuscular junction (NMJ) is a synapse with one of the highest safety margins in the human body. The use of neuromuscular blocking agents to inhibit neuromuscular transmission is sufficient to produce skeletal muscle paralysis, a mechanism used to facilitate muscle relaxation during surgery. …
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Modelling and investigating treatments of childhood inherited mitochondrial diseases in zebrafish.
… patient disease features, including a neuromuscular transmission defect, helping to strengthen the disease genotype-phenotype correlation and highlight the neuromuscular junction as feature of mitochondrial disease.
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The Level of Antiacetylcholine Receptor Antibodies in the Patients with Myasthenia Gravis
… loss, damage of the postsynaptic membrane at the neuromuscular junction, and failure of the neuromuscular transmission. These make the myasthenia gravis (MG) which may cause ptosis, diplopia, dysarthria, dysphagia, generalized weakness, or even respiratory failure. In the previous studies level of …
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Transmission at the mammalian neuromuscular junction
… techniques were evolved. The concept of the neuromuscular junction as a physiological entity dates from the researches of Claude Bernard on in 1850-57. The work of Langley (1950, 1907) indicated the pharmacological specificity of the muscle junctional region. Following the demonstration of …
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Transmission at the mammalian neuromuscular junction
… techniques were evolved. The concept of the neuromuscular junction as a physiological entity dates from the researches of Claude Bernard on in 1850-57. The work of Langley (1950, 1907) indicated the pharmacological specificity of the muscle junctional region. Following the demonstration of …
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Identifying the molecular basis for treatment resistance in a subset of myasthenia gravis patients of African ancestory
… of the muscle endplate resulting in failure of neuromuscular transmission and fatigable weakness. We have previously shown that a subpopulation of South African MG patients of African genetic ancestry develop a severe extraocular muscle (EOM) phenotype whilst receiving standard immunosuppressive …
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The effects of anticholinergic drugs on sea anemones
… from acetic acid and choline at the neuromuscular junction (Figure 2) in the presence of energy. The energy is obtained as a result of the action potential produced by the nerve impulse traveling along the nerve to the neuromuscular junction.</p><p>The acetylcholine proceeds to cross …
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Treatment-resistant ophthalmoplegia in Myasthenia gravis: extraocular muscle pathology, the role of TGFβ1 and the derivation of induced pluripotency towards 'disease-in-a-dish' modeling
… in which pathogenic antibodies target specific neuromuscular junction proteins, most frequently acetylcholine receptors (AChR). Among those without detectable AChR-antibodies, a subgroup of patients has antibodies directed against muscle-specific tyrosine kinase (MuSK). In MG the pathogenic …
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Enfermedades de la placa neuromuscular
… se describen las enfermedades de la placa neuromuscular, su epidemiología, hallazgos clínicos, métodos diagnósticos y tratamiento de cada una de ellas