Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"Neuromuscular disorders"”.
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Fatigue in neuromuscular disorders and chronic fatigue syndrome - a neurophysiological approach.
Contains fulltext : 27023.pdf (Publisher’s version ) (Open Access)
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Tracking individual disease-trajectory of patients with neuromuscular disorders (Duchenne muscular dystrophy and spinal muscular atrophy)
Neuromuscular diseases represent a diverse group of complex genetic disorders. In conditions such as Duchenne muscular dystrophy (DMD) and Spinal muscular atrophy (SMA), progressive motor impairment limiting activities of daily life is a common and central clinical feature. Over the last 15 years, …
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Model Based Decomposition of MUAPS Into Their Constituent SFEAPS
… of the motor unit that takes place due to disorders affecting peripheral nerve and muscle. MUAP features extracted in the time domain like duration, amplitude and phases are extensively used by the neurophysiologist for the assessment of neuromuscular disorders. In this study, a model based …
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Relationship between Surface and Indwelling EMG Spike Shape Measures
… for monitoring human movement and detecting neuromuscular disorders. The present study analyzed the relationship between surface and indwelling EMG interference patterns. Twenty four males and twenty four females performed three isometric dorsiflexion contractions at five force levels from …
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Proteomic Profiling of Animal Models of Motor Neuron Disease and Muscular Dystrophy
… in the identification of novel biomarkers of neuromuscular disorders and the elucidation of new pathobiochemical mechanisms that underlie these diseases. Detailed mass spectrometryQbased analysis of various diseased muscle groups from animal models of motor neuron disease and XQlinked muscular …
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P300-Based BCI Performance Prediction through Examination of Paradigm Manipulations and Principal Components Analysis.
<p>Severe neuromuscular disorders can produce locked-in syndrome (LIS), a loss of nearly all voluntary muscle control. A brain-computer interface (BCI) using the P300 event-related potential provides communication that does not depend on neuromuscular activity and can be useful for those with LIS. …
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Motor neurone and muscle nuclear changes in development and disease
The primary gene defects of hereditary neuromuscular disorders have not, as yet, been determined. Research has contributed much to our understanding of many aspects of these diseases, but since this has been directed towards the secondary phenomena, the exact role of the nucleus in the pathogenesis …
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Assessing patient and caregiver intent to use mobile device videoconferencing for remote mechanically-ventilated patient management
… Ventilation Clinic (AVC) supports patients with neuromuscular disorders and spinal cord injuries and their caregivers at home, helping them avoid expensive emergency department visits, hospitalization, and unnecessary or excessive treatments. Mobile device videoconferencing provides an effective …
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A statistical framework for the analysis of neural control of movement with aging and other clinical applications
… to understand the mechanisms involved in normal neuromuscular aging. The objective of the research is to understand the effects of aging on biological signals for motor control and to develop a methodology to classify aging and stroke populations. The methodological approach investigated the …
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RF SENSORS FOR MEDICAL AND CYBER-PHYSICAL INTELLIGENCE
… sensor has also been applied to prevalent sleep disorders such as apnea and hypopnea. Another aspect of my research focuses on muscle monitoring. Conventional electromyography (EMG) measures the neural activity during muscle contraction, but lacks explicit quantification of the actual …
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Acute and Chronic Effects of Botulinum Toxin Type-A on the structure and Function of the Quadriceps Femoris Muscles of New Zealand White Rabbits
… a common treatment modality for a variety of neuromuscular disorders with the primary aim to relax spastic muscles, for example, in children with cerebral palsy, or following a stroke. Once injected, BTX-A prevents acetylcholine release at the motor nerve endings, thereby producing a …
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Individual plantar flexor compensation during walking with a unilateral passive dynamic ankle-foot orthosis : a simulation study
… in persons with a variety of musculoskeletal and neuromuscular disorders. Passive dynamic AFOs (PD-AFOs) are a special class of orthoses that function like a torsional spring, which store elastic energy in early stance and release that energy in late stance to supplement impaired muscle (e.g. …
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Investigation of bench methods for determining stiffness of solid ankle-foot orthoses
… most common treatment for the compensation of neuromuscular disorders usually caused by stroke and spinal cord or peripheral nerve injuries. The biomechanical functions of plastic AFOs are determined by their thickness, the material selection and their geometry. The geometry, also known as …
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Evaluation of Global Muscle Innervation Using Multi-Channel Surface Electromyography
… have enabled the non-invasive assessment of neuromuscular function at the muscle and motor unit level. Specifically, sEMG has been used to assess the location of innervation zones (IZs) and the quantity of functioning innervation of targeted muscles. This knowledge associated with muscle …
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THE APPLICATION OF RADIOFREQUENCY WAVES IN THE MANAGEMENT OF ORAL MAXILLOFACIAL PAIN
Temporomandibular disorders (TMDs) represent a common and complex clinical condition, defined by the American Academy of Orofacial Pain as a group of muscular and neuromuscular disorders which affect the temporomandibular joint (TMJ) and those structures connected to it. These disorders involve …
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A role for RNA localization in the human neuromuscular disease myotonic dystrophy
… These data have apparent application to several neuromuscular disorders and open a plethora of novel research avenues, both basic and applied.
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Developing mouse complex I as a model system: structure, function and implications in mitochondrial diseases.
… in both sets of subunits result in severe neuromuscular disorders such as Leigh syndrome. Several structures of mammalian complex I from various organisms have been determined, but the limited resolutions of the structures, which typically refer to poorly characterised enzyme states, has …
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Mitochondrial Dysfunction and Stress Responses in CHCHD10 Myopathy and Neurodegeneration
… Different mutations in CHCHD10 cause additional neuromuscular disorders, including the lower motor neuron disease spinal muscular atrophy Jokela type and autosomal dominant isolated mitochondrial myopathy. Modelling these disorders is revealing how mitochondrial dysfunction contributes to the …
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Toward an Optical Brain-computer Interface based on Consciously-modulated Prefrontal Hemodynamic Activity
… may potentially benefit individuals with severe neuromuscular disorders who experience significant, and often total, loss of voluntary muscle control (e.g. amyotrophic lateral sclerosis, multiple sclerosis, brainstem stroke). Though a majority of BCI research to date has focused on …
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The effects of nutritional supplementation on regeneration of muscle function after damage
… conditions, weakness associated with aging, neuromuscular disorders, acquired immunodeficiency syndrome, burn injury, cancer cachexia and prolonged sepsis.
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