Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 79 for “"Neurological conditions"”.
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Monitoring and Treating Neurological Conditions Through Focal Interfacing with the Brain
Neurological dysregulation serves as the fundamental basis for a spectrum of debilitating disorders such as Parkinson's disease and epilepsy. Despite considerable efforts, our current comprehension of these disorders and ability to treat them remains limited. Neurochemical sampling of the affected …
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Occupational Therapists' Perceptions and Clinical Reasoning of Splints Used in Adults with Neurological Conditions
… for upper extremity functional improvement in neurologically impaired patients is a common practice among occupational therapists despite inadequate evidence to support this intervention. This mixed-method study aims to address the gap in research regarding occupational therapists’ perceptions …
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Developing volunteering as an intervention for social isolation in those with long-term neurological conditions
… Participation in life situations in People with neurological conditions (pwNC) is often restricted due to physical, social and environmental factors. Social isolation is common and has been associated with increasing feelings of depression and apathy and reduced life expectancy. Opportunities for …
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A DLK And JNK Dependent Axon Self-Destruction Program Promotes Wallerian Degeneration
… is a debilitating consequence of a wide range of neurological conditions. As axons degenerate, they go through a stereotyped sequence of morphological changes termed Wallerian degeneration. It has long been hypothesized that there is an active axonal breakdown program, conceptually similar to …
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Improving visio-motor coordination in non-dominant hands through tracing tasks
… tasks. These skills can be impaired in several neurological conditions. Effective rehabilitation schemes are needed in order to improve visuo-motor coordination in such subjects. This study will propose and test a training regimen as a potential approach for improving fine eye-hand coordination. …
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RhoA and Rac1 prenylation: Effects on serine/threonine signaling for actin polymerization
… of Rho GTPases is implicated in several neurological conditions. Rho GTPases are activated by binding to guanosine triphosphate (GTP) and is thought to require translocation to the plasma membrane by the addition of an isoprenoid moiety (geranylgeranyl) to the protein. However, previous …
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An in vitro study to characterize a new automated high throughput neuronal stretch injury system
… (TBI) is one of the most prevalent long-term neurological conditions and its overall economic consequences rival that of stroke. Considering the importance of the topic, new models for studying TBI are often designed and created. Based on a model developed by the University of Pennsylvania, …
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Characterizing CMT-causing variants in tryptophanyl- tRNA synthetase
… that link amino acids to their cognate tRNAs. Neurological conditions, such as Charcot-Marie-Tooth (CMT) disease, have been linked to variants identified in these enzymes. I created a humanized yeast model to assess the underlying disease-causing mechanism associated with two CMT variants, …
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The Vernacularisation of Modern Neurosciences: A Case Study of Neuro-Autobiographies in The Age of Complexity
… written by professional women with neurological conditions which are coined here as neuro-autobiographies. The interaction between the neuroscientific knowledge and the autobiographers lived experience with a brain condition contributes to a complex process of life-writing and …
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The Moderating Effect of Physical Activity on the Association between White Matter Hyperintensities and Gait Characteristics
… individuals in presence and absence of overt neurological conditions and 2) to evaluate whether physical activity (PA) moderated the association between WMH and gait velocity and stride time variability (STV), under single and dual-task conditions, in a geriatric clinic sample. Study 1 …
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Modulating Neuroinflammation with Porous Templated Scaffolds
… mobility and independence for patients with neurological conditions such as spinal cord injury, stroke, or limb loss. However, unstable neural recording performance remains unresolved. Via the foreign body reaction, macrophages and glial cells develop a “glial scar” around implants, …
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Genetic Testing Practices of Genetic Counselors, Geneticists, and Pediatric Neurologists With Regard to Childhood-Onset Neurogenetic Conditions
<p>Identifying genetic diagnoses for neurological conditions with a considerable hereditary component, such as autism spectrum disorder (ASD), intellectual disability, and epilepsy, is critical to providing proper medical management for these patients and their families. However, many patients with …
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Transforming physiotherapy education: exploring co-designed neurological rehabilitation student-led clinics through the dual lens of student and service user perspectives.
Background - Physiotherapy neurological student-led clinics (SLCs) are innovative educational settings where students lead the provision of rehabilitation for patients with neurological conditions, under the supervision of qualified staff. Student-led clinics can offer dual benefits: enhancing …
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An embedded device for real-time noninvasive intracranial pressure estimation
… of intracranial pressure (ICP) is key in many neurological conditions for diagnosis and guiding therapy. Current monitoring methods are highly invasive, limiting their use to the most critically ill patients. Based on a previously developed approach to noninvasive ICP estimation from cerebral …
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Factors Influencing the Face Validity of Effort Tests: Timing of Warning and Feedback
… were undergraduate students without a history of neurological conditions, mental health concerns, or current problems with alcohol or drug use. The goal of Experiment 1 was to determine whether the timing of a warning that some tests may detect faking would influence (the face validity of and …
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Factors Influencing the Face Validity of Effort Tests: Timing of Warning and Feedback
… were undergraduate students without a history of neurological conditions, mental health concerns, or current problems with alcohol or drug use. The goal of Experiment 1 was to determine whether the timing of a warning that some tests may detect faking would influence (the face validity of and …
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A Diagnostic and Prescriptive Conformal Prediction Framework: Applied to Sleep Disorders
… future diagnoses and treatments of patients with neurological conditions, specifically patients with sleep disorders, given their clinical history. Via the use of a conformal algorithm with a classifier as its base model, we are able to utilize a patients history of diagnoses, pharmacy dispensing, …
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Neuropsychological Profiles in Temporal Lobe Epilepsy With and Without a History of Traumatic Brain Injury
… are consistently observed. Even though these two neurological conditions are intertwined, very little is known about the combined effects on neurocognitive functioning. This study aimed to examine neuropsychological functioning in TLE patients with and without a history of TBI. It was predicted …
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Magneto-rheological fluid orthosis for suppressing tremor
… movement disorder that occurs with specific neurological conditions. This condition may seriously impact daily living activities. The aim of the present study is to evaluate the possibility of the development of a wearable technology that is capable of exerting torques at a user's joints for …
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Brain states and circuit mechanisms underlying sleep and general anesthesia
… to advancing treatments of sleep disorders and neurological conditions such as coma. In this thesis, I combine intracranial electrophysiology in human subjects with optogenetic manipulation of thalamocortical circuits in mice to identify the neural dynamics underlying sleep and anesthesia. I …
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