Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Neurologi"”.
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An Associative Memory Trace in the Cerebellar Cortex
Classical conditioning of motor responses, e.g., the eyeblink response, depends on the cerebellum. In the theoretical works of David Marr (1969) and James Albus (1971), it was proposed that Purkinje cells in the cerebellar cortex learn to associate the neutral conditioned stimulus with the …
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Multiple Sclerosis: Studies of the Interferon system and search for infectious agents
Multiple sclerosis (MS) is a chronic disease of the central nervous system, characterized by focal inflammatory lesions with demyelination and axonal loss. It is believed that MS is an immune-mediated disorder with both genetic and environmental contributions to the pathogenesis. Interferons (IFNs) …
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Novel Immunotherapies and Immunoregulation in a Chronic Inflammatory Disease of the Central Nervous System
Multiple sclerosis (MS) is a chronic inflammatory disease of central nervous system (CNS) which is thought to arise from a breakdown of immunological tolerance in CD4 cells. The aim of this thesis is to improve our understanding of regulation mechanisms of T cell-dependent chronic inflammation in …
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Mitochondrial permeability transition following calcium overload. - Its role in neuronal cell death and potential as a pharmacological target.
… properties in several different animal models of neurological disease, and recent experiments subjecting mice lacking CypD to ischemia support the conclusion that the effect of CsA at least in this model is mediated by mPT inhibition. A library of CsA analogs was evaluated for mPT-inhibiting and …
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STRENGTH TRAINING AFTER STROKE: EFFECTS ON MUSCLE FUNCTION, GAIT PERFORMANCE AND PERCEIVED PARTICIPATION
The overall aim of this thesis was to evaluate the effects of strength training on muscle function, gait performance and perceived participation in subjects with chronic mild to moderate post-stroke hemiparesis. A main impairment after stroke is reduced muscle strength. This post-stroke weakness is …
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Ontogenetic and comparative aspects of cerebellar and motor development
During the course of development the motor repertoire of animals and humans alike go through dramatic changes. New motor patterns arise; movements become coordinated, improve in precision and are at the same time continuously calibrated to the changing body dimensions. The cerebellum is critical …
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Hypertension, blood pressure, cognition and cerebral blood flow in the cohort of "Men born 1914"
"Men born 1914" is a population based cohort study of the epidemiology of cardiovascular disease. Five hundred men, born 1914, were examined at the age of 68 and 185 of them were re-examined at 81 years of age. Examination included a medical and a psychological investigation, ultrasonographic …
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Clincal Aspects of Biological Brain Damage Markers
… Daily S100B levels did not predict secondary neurological complications or outcome in the neurointensive care unit. Serum GFAP and APC-PCI measurements, prior to neuroimaging, had a 97% negative predictive power for haemorrhagic stroke and a 100% value if only samples within 12 hours were …
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Distribution and function of TRP ion channels in primary sensory neurons
It is frequently argued that cannabinoids exert part of their analgesic and anti-inflammatory effects via activation of the cannabinoid CB1 receptor located on TRPV1-expressing primary sensory nerve fibres in peripheral tissues. However, we find no evidence of CB1 receptor immunoreactivity on nerve …