Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"Neuroendocrine Prostate Cancer, Synthetic Dosage Lethality"”.
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Finding the Best Gene Candidate(s) as a Potential Therapeutic Target for N-MYC Overexpressing Neuroendocrine Prostate Cancer (NEPC)
Neuroendocrine prostate cancer (NEPC) is the most aggressive form of prostate tumorigenesis. Recent studies have shown that one of the key genes that regulate the development of NEPC cells is the N-MYC oncogene, along with the loss of tumor suppressors such as TP53 and RB1 (Lee et al., 2016). …