Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 205 for “"Neuroendocrine"”.
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Mathematical modelling of pulsatility in neuroendocrine systems.
The work described in this thesis concerns the mathematical description of the characteristic oscillatory electrical behaviour of certain neurosecretory cells found in the hypothalamus of the mammalian brain. This study concentrates on those cells which secrete the hormone oxytocin. A model first …
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Analysis of ASCL1 in Neuroendocrine Lung Cancer
… is an understudied tumor subset with aggressive neuroendocrine carcinoma features. Previous studies have determined that the basic helix-loop-helix (bHLH) transcription factor achaete-scute homolog 1 (ASCL1) is essential for the survival and progression of many pulmonary neuroendocrine (NE) …
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Gallium-68 DOTATATE PET/CT in Neuroendocrine Tumors
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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The Effects of Neuroendocrine Stress on Larval Development
Environmental stressors are ubiquitous. Animals will face a variety of natural and anthropogenic stressors throughout their life cycle. The physiological mechanisms that mediate stressful stimuli can have pleiotropic effects on life history traits, such as reproduction and development. Furthermore, …
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The Role of GABA in Reproductive Neuroendocrine Systems
<p>Local gamma-amino butyric acid (GABA) neurons in the hypothalamus can modulate the luteinizing hormone releasing hormone (LHRH) pulse generating system.</p> <p>Two animal models (intact and ovariectomized rats) were used to determine the nature of modulation of LHRH release by GABA. The …
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Metabolic signalling and neuroendocrine stress responses in pregnancy
… during exposure to a stress, to which reduced neuroendocrine stress responses may contribute. Glucocorticoids have a key role in mobilising energy in response to acute stress, and have longer-term actions in the regulation of fat storage. I investigated the relationship between the HPA axis and …
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Neuroendocrine regulation of broodiness in the domestic hen
… between these hormones and neuropeptide in the neuroendocrine control of incubation behaviour in the domestic hen. Observations were made using fluorescence immunocytochemistry with additional data on progesterone receptor mRNAs, using PCR to localize the receptor. Hypothalamic progesterone …
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Regulation Mechanisms of Peptide Hormones in Neuroendocrine Cancers
In the work described in this thesis, analytical methods for the detection and quantification of peptide hormones featuring on-line analyte concentration, post-separation tagging and HPLC-fluorescence detection were presented. These methods were used to detect and quantify calcitonin (CT) and its …
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Regulation Mechanisms of Peptide Hormones in Neuroendocrine Cancers
In the work described in this thesis, analytical methods for the detection and quantification of peptide hormones featuring on-line analyte concentration, post-separation tagging and HPLC-fluorescence detection were presented. These methods were used to detect and quantify calcitonin (CT) and its …
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Neuroendocrine mechanisms of behavioral changes induced by hypoglycemia
Hypoglycemia is associated with a variety of adverse behaviors including fatigue, confusion, social withdrawal, anhedonia and depressive-like behaviors. While these clinical symptoms are well characterized, the mechanisms of their cause are not understood. Here, we investigated how insulin-induced …
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Characterizing ASCL1-Dependent Neuroendocrine Non-Small Cell Lung Cancers
… decades suggest that distinct, poorly performing neuroendocrine tumors occur in about 10% of otherwise pathologically indistinguishable non-small cell lung cancers. A complete molecular characterization of these tumors is lacking because no pre-clinical model exists. Utilizing genome-wide mRNA …
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Neuroendocrine Function of Female Youth with Callous-Unemotional Traits
… to continue offending in adulthood. Disordered neuroendocrine function may be a mechanism for the development of CU traits. We examined whether altered stress responsivity served as a mechanism linking stress exposure and the expression of CU traits. Participants were 15 incarcerated adolescent …
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Maternal Behavior in the Rat: Neuroendocrine and Neuroanatomical Substrates
… that constitute this functional pathway nor the neuroendocrine events triggered by the estrogenic signal have been defined. The first set of studies described in this thesis (Chapter 2) employed a method combining steroid hormone autoradiography and fluorescent dye retrograde tracing to …
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Analysis of intracellular Ca2+ oscillations in a neuroendocrine cell
Contains fulltext : 147080.pdf (Publisher’s version ) (Open Access)
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Reciprocal Relationships Between the Neuroendocrine System and Lymphoid Cells
A wide variety of environmental and psychological stressors alter the susceptibility of animals to infectious and neoplastic diseases. However, physiologic mechanisms involved in these phenomena are not understood. Acute stressors activate both the hypothalamic-pituitary-adrenal axis and …
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The neuroendocrine mechanism of reproductive photorefractoriness in the ewe
… of this study was to explore the possible neuroendocrine mechanisms of reproductive photorefractoriness using pharmacological and neurosurgical approaches. Ovary-intact (INTACT), ovariectomized (OVX) and ovariectomized estradiol-treated (OVX + E$\sb2$) ewes were subjected to 3 different …
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Behavioural, neurochemical and neuroendocrine effects of predator stress in mice
… parameters in various brain regions and on neuroendocrine parameters in mice. Therefore mice of several strains were exposed to a rat. Also the effects of repeated predator exposure were assessed. Rat exposure lead to risk assessment behaviour, followed by coping strategies. Extracellular …
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Neuroendocrine Events Associated With Sexual Stimulation of the Dairy Bull
Made available in DSpace on 2014-12-14T15:29:41Z (GMT). No. of bitstreams: 1 8009203.pdf: 4777516 bytes, checksum: 9e767631f3fbebc3e0bf3df9bacd1851 (MD5) Previous issue date: 1979
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