Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Neurocognitive impairment"”.
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Blood-Based Inflammation Biomarkers of Neurocognitive Impairment in People Living with HIV
… living with HIV (PLWH) experience HIV-associated neurocognitive disorders (HAND). ART has decreased incidence of HAD but the less severe forms of HAND has increased. Diagnosis of HAND is challenging as the often-subtle forms of impairment are not as overt as dementia. HIV infection promotes …
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Hypertension and Neurocognitive impairment as measured by the Zambia Neurobehavioural test battery--A pilot study
… However the effect of hypertension on neurocognitive functioning has received less attention in research. Some studies (e. g Starr, Deary, Fox & Whalley (2006) have reported deficits in some domains of cognition, while others (e. g. Huang et al., 2009) have reported no significant …
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The Influence of Neurocognitive Impairment on Treatment Outcomes among Drug-involved People Living with HIV/AIDS
… system and this can result in neuro-cognitive impairment. In combination, their effects can be even more profound and this is directly relevant to intervention development because a significant number of people living with HIV/AIDS have a positive history of substance abuse. AIM: To evaluate if …
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Neurocognitive impairment following central nervous system infections in Kenyan children as detected by event related potentials
… related potentials (ERPs) can be used to detect neurocognitive impairment following the most common central nervous (CNS) system infections affecting children in sub-Saharan Africa, namely falciparum malaria, acute bacterial meningitis (ABM) and human immune-deficiency virus (HIV). Four groups of …
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Integrating HIV-associated neurocognitive impairment screening and health services within primary healthcare facilities in South Africa
… comorbidities including HIV-associated neurocognitive impairment (H-NCI). These individuals may then be at an increased risk for treatment non-adherence, which leads to poor quality of life and early mortality. Despite this risk, there is a paucity in trained professionals in low- and …
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Assessing type 2 diabetes associated NeuroCognitive impairment using an e-screening tool in a South African population
… has been found to be associated with cognitive impairments in planning, problem solving, organization, and working memory and also with an increased risk of dementia. Neurocognitive impairment may impact self-care and other health behaviours increasing the risk of poor health outcomes in this …
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Blood and Lumbar Fluid Biomarker Changes in Patients with HIV-Associated Neurocognitive Impairment Treated with Lithium: Analysis from a Randomised Placebo-Controlled Trial
HIV-associated neurocognitive disorders (HAND) persist in the era of antiretroviral therapy (ART). Thus, ART does not completely halt or reverse the pathological processes behind HAND. Adjuvant mitigating treatments are therefore prudent. Lithium treatment is known to promote neuronal brain-derived …
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A cross-sectional study of the association between cognitive impairment and haemoglobin levels in HIV-infected South Africans established on antiretroviral therapy
… as a potential risk factor for HIV-associated neurocognitive impairment. The association between haemoglobin levels and neurocognitive function has not been assessed in a Sub-Saharan study population in the era of ART. Methods A cross-sectional secondary data analysis was performed to assess …
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Pre-treatment of patients undergoing cardiopulmonary bypass with hyperbaric oxygen : a prospective randomised double-blind evaluation of inflammatory response and neurocognitive outcome
… Despite these improvements subtle neurocognitive impairment, from diffuse cerebral injury due to micremboli during cardiopulmonary bypass, continues to occur following cardiac surgery.Previous human and animal studies have shown that hyperbaric oxygen can reduce some of the …
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DTI, structural network connectivity, and neurocognitive changes associated with subconcussive impacts in youth football players
… (WM) microstructural integrity and lead to neurocognitive impairment. Little is known, however, about the effects of cumulative repetitive head impacts, or so-called subconcussive head impact exposure. Neuroimaging analyses of youth athletes may allow characterization of potential …
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The effect of HIV-1 Tat and methamphetamine on expression of cytokines/chemokines and synaptic genes: Implications in HIV neuroAIDS
… cognitive dysfunctions, including asymptomatic neurocognitive impairment (ANI) and Mild neurocognitive disorder (MND). These neurological deficits affect approximately 50% of HIV-1 infected people. The neurotoxicity of HIV-1 has been attributed to the virus itself or the viral proteins like …
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Feigning Cognitive Deficits on Neuropsychological Evaluations: Multiple Detection Strategies
… frequently stand to gain in some manner if neurocognitive dysfunction is diagnosed. As a result, neuropsychologists are customarily asked to test for neurocognitive feigning during the assessment. The current study employed an analogue design with a clinical comparison group to examine the …
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The Impact of Marijuana Use on Memory in Patients with HIV/AIDS
<p>The most robust neurocognitive effect of marijuana use is memory impairment. Memory deficits are also high among persons living with HIV/AIDS, and marijuana use among this population is disproportionately common. Yet research examining neurocognitive outcomes resulting from co-occurring …
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The role of the astrocytic marker S100B in HIV-associated neurocognitive disorders
… are as yet no ideal biomarkers of HIV-associated neurocognitive disorders. As astrocytosis is a feature of HIV encephalitis, the marker S100β may hold promise as a biomarker of HAND. We explored associations between S100β and neurocognition in individuals with HIV in Cape Town, South Africa, …
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Head Acceleration Experienced by Man: Exposure, Tolerance, and Applications
… was once considered to only result in immediate neurocognitive impairment and symptoms that are transient in nature, recent research has correlated long-term neurodegenerative effects with a history of sports-related concussion. Increased awareness and current media attention have contributed to …
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Screening for HIV-associated neurocognitive disorders in perinatally infected youth: Validation of the CAT-rapid version 2 screening tool
… Tool Rapid v2 tool in screening for all forms of neurocognitive impairment in a sample of youth living with HIV in Cape Town, South Africa. Design: We analysed the existing dataset of the neuro sub-study which was nested within the larger CTAAC study (Cape Town Adolescent Antiretroviral Cohort). …
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The short-term effects of off-pump cardiopulmonary bypass graft surgery on cognitive performance
Postoperative neurocognitive impairment has been associated with coronary artery bypass graft surgery (CABG). This study investigates the short-term effects of off-pump cardiopulmonary bypass graft surgery (OPCAB) on cognitive performance, as a possible safer alternative in the treatment of …
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Evaluation of Football Safety Techniques Utilizing Biomechanical Measurements
… that the injury can also result in long term neurocognitive impairment. Thus, there is much needed research to better understand concussions and assist in the development of safety techniques that will reduce the occurrence of such injury. Participants of youth football are at an extreme …
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An investigation of a neuro-inflammatory profile of HIV-associated neurocognitive disorders
Background HIV-associated neurocognitive disorder (HAND) is the consequence of the effects of HIV-1 within the central nervous system (CNS). HIV-associated neurocognitive impairment differs in severity with milder forms presenting in 50% of people living with HIV (PLWH), regardless of treatment …
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Factors affecting metabolism and metabolic control in phenylketonuria
… phenylalanine restricted diet in order to avoid neurocognitive impairment. Blood phenylalanine is the main outcome marker which is modulated by many dietary factors. Traditionally, L-amino acid-based protein substitutes are the main nitrogen source but more recently glycomacropeptide-based …
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