Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Neurochemicals"”.
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Novel tool for sampling in vivo neurochemicals from the central nervous system.
Novel tool for sampling in vivo neurochemicals from the central nervous system.
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Normalization of Cerebral Blood Flow, Neurochemicals, and White Matter Integrity After Kidney Transplantation
… KT also normalized concentrations of osmotic neurochemicals choline (p<0.0001) and myo-inositol (p=0.0003) that were higher pre-KT compared to controls. Post-KT, FA increased (p=0.001) and MD decreased (p=0.0001). Conclusions: Brain abnormalities in CKD are reversible and normalize with KT. …
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Detection and Imaging of Neurotransmitters in Rodent Brain Tissue Using FMP-10 and ZnO Nanoparticle Matrices with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
… on-tissue chemical derivatization to detect 17 neurochemicals, notably dopamine, γ-aminobutyric acid (GABA), serotonin, and norepinephrine. ZnO NP detects 9 neurochemicals, including glutamate and glutamine, which are undetectable by FMP-10. We applied both matrices to investigate neurochemical …
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Nanoporous dialysis membrane for microfluidic neural probes
… between cells in the brain is mainly via neurochemicals, the detection of neurochemicals is vital to understand brain functionality. Neural probes, as a microscale implant for brains, can be used to detect the neurochemicals. Among various kinds of neural probes, dialysis neural probes …
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Serotonin and Norepinephrine in Latent Inhibition.
… have enabled more detailed manipulations of neurochemicals. These discrete changes in neurotransmitter levels have been linked to changes in behavior. Depletions of the neurotransmitters norepinephrine and serotonin have been demonstrated to alter associative processes in the rat. This study …
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Breaking Away: The Role of Homeostatic Drive in Perpetuating Depression
… homeostasis. Through psychological activity, neurochemicals act as homeostatic regulators. This study proposes that these components are part of a regulatory system that is capable of supporting multiple homeostatic regimes that, in turn, give rise to self-sustaining psychological behaviors. …
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The Effect of Embryonic Alcohol Exposure on Brain Function and Behavior in Zebrafish Strains
… development of shoaling behavior and correlated neurochemicals in the absence of embryonic alcohol in order to establish baseline behavior. Next, I examined the effect of embryonic alcohol exposure on neurochemicals dopamine, serotonin and their metabolites and found embryonic alcohol to disrupt …
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Neurochemical Levels Correlate with Population Level Differences in Social Structure and Individual Behavior in the Polyphenic Spider, <em>Anelosimus studiosus</em>.
… Detection to quantify levels of these neurochemicals among adult females from social (multi-female) and solitary (single-female) webs in east Tennessee. A subset of spiders was scored for individual social tendency. We found that higher octopamine levels are associated with a greater …
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The Effect of Organophosphate Exposure on Neocortical, Hippocampal and Striatal Monoamines: A Potential Substrate for Chronic Psychiatric, Cognitive and Motor Dysfunction
… differences in concentration of monoamine neurochemicals were observed between vehicle control and CPS-treated groups in either the hippocampus or striatum. However, in the frontal cortex of the CPS-treated rats there was a significant increase in median dihydroxyphenylacetic acid (DOPAC) …
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Systemic administration of putrescine induces GABA-like behaviors in rats
… related to the function of GABA and/or other neurochemicals. Experiment 3 investigated the modifying effects of putrescine treatment on behavior induced by a dopamine agonist, apomorphine, and were compared to effects produced by a GABA agonist, muscimol. Male adult rats were given either …
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Behavioural, neurochemical and neuroendocrine effects of predator stress in mice
… a selective activation of brain regions and neurochemicals. This highly differentiated response may be of utmost importance to coordinate and to fine-tune the specific neuroendocrine, behavioural and autonomic responses to this form of stress. It might be worthwhile to increase the stressful …
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Chemical Genetic Interrogation of Neural Stem Cells: Phenotype and Function of Neurotransmitter Pathways in Normal and Brain Tumor Initiating Neural Precursor Cells
… Specifically, I first evaluate the effects of neurochemicals in mouse models of brain tumors. I then outline a retrospective meta-analysis of brain tumor incidence rates in psychiatric patients presumed to be chronically taking neuromodulators similar to those identified in the initial screen. …
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Miniaturized silicon platform with high spatial, temporal and chemical resolution for cortical neurochemical gradients studies
… demonstrating how the understanding of neurochemicals could be improved with the higher spatial resolution and less disturbance. The localized sampling and neurochemical analysis would be discussed in Chapter 4. And based on the platform’s current development and integration strategy, …
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Silicon processing for microfluidic neuroprobes
… in this system is the concentration profile of neurochemicals as they are the basis of all neural activities. To obtain these measurements in awake subjects, a neuroprobe capable of extracting neuromodulators with high temporal and spatial resolution and high chemical sensitivity and selectivity …
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Development of Electrochemical Sensors Suitable for In Vivo Detection for Neurotransmitters
… in expanding the detection to other important neurochemicals, showed that commonly used drop-casting techniques deposit nanoparticles non-uniformly. More reproducible modification methods are needed. The work in this dissertation demonstrates the capabilities of redox cycling for …
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Neurochemical monitoring by silicon nanodialysis probe coupled with mass spectrometry detection
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-08-01
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Using prophylactics to improve resistance against Enterobacteriaceae in chickens
… alone (ex: shifts in the gut microbiota and neurochemicals) are sufficient to induce anti-Enterobacteriaceae responses.</p>