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Showing 1 to 1 of 1 for “"Neuroblastoma, XIAP, apoptosis, treatment, degradation, ARTS mimetic"”.
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DEGRADATION OF XIAP AS A NOVEL TREATMENT STRATEGY IN HIGH-RISK NEUROBLASTOMA
The potential of XIAP antagonism as a treatment strategy for neuroblastoma has not been investigated despite neuroblastoma being an embryonal cancer with a developmental biology requiring XIAP. Here, we showed that the targeting of XIAP, and not other IAP members such as c-IAPs, was necessary to …