Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 108 for “"Neural circuitry"”.
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Neural Circuitry of Social Valuation
… across three independent studies, I focus on the neural circuitry supporting social valuation — which shapes our social interactions and interpersonal choices. In the first study (Chapter 2), I demonstrate that social valuation relies on the posterior ventromedial prefrontal cortex (pVMPFC). …
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Optical photoreceptors for CMOS neural circuitry.
… will be used to provide optical inputs to a neural network. By using optical connections to provide inputs to the chip, data can be sent directly to individual locations on the chip from above. This approach may eventually be used to solve the problems of an analog storage device and of …
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Dopaminergic modulation of hippocampal neural circuitry
Memory is a limited resource. Therefore, the circuitry that encodes memory must filter incoming information in accordance with its perceived value. The hippocampus, the hub of the declarative memory system, may achieve memory valuation using its rich variety of neuromodulatory afferent systems. The …
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Neural Circuitry Deficits Associated With Dysfunctional Myelin
… study on the impact of dysfunctional myelin on neural processing.</p> <p>Undoubtedly, slowed conduction velocity along myelinated axons increases temporal dispersion and, consequently, degrades information transfer between neural circuits. Herein, this dissertation work explores the impact of …
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The Neural Circuitry Of Social Behavior In C. elegans
… as a model system to study the genetics and neural circuitry that underlie social behavior. First, I evaluated the behavioral responses of C. elegans to a nematode extract (deathmone), which served as a model for alarm pheromones in other animal species (chapter 2). Worms showed acute …
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Linking dopaminergic physiology to working memory related neural circuitry
… thought to be encoded in the brain by persistent neural activity that outlasts the presentation of a stimulus. Interestingly, patients with schizophrenia, a heritable neurological disorder, perform poorly in working memory tasks that require the retention of a target in space, indicating that …
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Appetite Regulatory Neural Circuitry in the Prenatal Testosterone Treated and Obese Ewe
… transcript (CART). We then asked whether this circuitry is altered in ewes at increased risk of obesity following prenatal testosterone (T) treatment, or in diet-induced obese ewes. Using immunocytochemistry, we found that prenatal T-treated ewes showed increased expression of the appetite …
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New Methods for Characterizing the Complex Neural Circuitry of the Adult Drosophila Brain
… permit unprecedented resolution for study of neural circuitry formation in Drosophila melanogaster. This study utilizes new mosaic methods to investigate conserved mechanisms that underlie the development of adult-specific neurons. In addition to providing several novel insights about the …
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A functional MRI study of the distributed neural circuitry of learning and reward
The aim of this research project was to study the neural substrates involved in processing rewarding stimuli. Evaluation of the magnitudes of reward is one of the fundamental aspects of goal directed behavior, and studies have shown that this process involves the midbrain dopamine system. Work by …
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DISSECTING THE NEURAL CIRCUITRY BEHIND SOCIAL DECISION-MAKING PROCESSES BY DIRECT AND OBSERVATIONAL LEARNING
… possibilità di analizzare in dettaglio le basi neurali dei processi decisionali sociali sia quando queste vengono apprese tramite apprendimento diretto sia tramite osservazione. Per il mio progetto di dottorato, abbiamo sviluppato un task decisionale in ambito sociale (SDM) in cui i topi possono …
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Neural circuitry in motion: Computational modelling of motor cortical dynamics to understand human movement
… of muscle activity remains elusive. Spiking neural networks (SNNs) represent the biological mechanisms of communication between neurons via action potentials. A SNN model containing over 38,000 neurons and 160 million synapses was developed to represent a 1 mm2 surface area of the motor …
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Elucidating the neural circuitry underlying social spacing in Drosophila melanogaster through the lens of neuroligin 3
… them, and the entire group. To understand the neural basis of complex social behaviour, we can study simpler behaviours that precede and mediate them. Social spacing, the typical distance between individuals in a group, is an easily quantifiable behaviour in Drosophila melanogaster. Here, I …
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The Influence Of Gender And Aging On The Neural Circuitry Supporing Facial Emotion Processing In Adults With Major Depressive Disorder
… (FEP). Previous studies investigating the neural substrates of these decrements have often reported hyperactivity of emotion processing circuitry. Neural circuitry supporting FEP has been shown to be different between healthy men and women, and between young and elder adults. However, no …
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Singing the Brain Electric
… have found, can treat depression by correcting neural circuitry gone haywire. This thesis examines how such technology - a technique known as deep-brain stimulation, in which electrodes are implanted within the brain - was developed and how it works. We are introduced to a patient who received …
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HORROR-EVOKED AROUSAL AND AMYGDALA BIAS OF THE MEDIAL TEMPORAL LOBE
… the relationship between threat-related neural circuitry during encoding of short movie clips to test temporal order memory and temporal distance memory. We measured neural circuitry in the medial temporal lobe (MTL), including the amygdala sub-nuclei areas of the basolateral and the …
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Dissociable Influence of Reward and Punishment Motivation on Declarative Memory Encoding and its Underlying Neurophysiology
… declarative memory encoding and its underlying neural circuitry. Chapter 1 provides a theoretical framework for investigating motivation's influence on declarative memory. This chapter will review the animal and human literatures on declarative memory encoding, reward and punishment motivation, …
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The Nature of the Processes, Representations, and Neural Substrates Which Support and Contribute to Motor Sequence Learning
… and are discussed in terms of the possible neural circuitry for motor sequence learning.
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The evolutionary emergence of neural organisation in computational models of primitive organisms
Over the decades, the question why did neural organisation emerge in the way that it did? has proved to be massively elusive. Whilst much of the literature paints a picture of common ancestry the idea that a species at the root of the tree of nervous system evolution spawned numerous descendants …
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Amygdalar Modulation of the Medial Geniculate Nucleus and Cingulate Cortex in Discriminative Avoidance Training
… of neurons in extra-amygdalar regions of the neural circuitry for DAL.
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