Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Neural Excitability"”.
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Distribution and regulation of ion channels in neurons: Quantitative studies of global ion channel transport and homeostatic synaptic scaling
… proteins are ion channels that modulate neuronal excitability, allowing neurons to fulfill their primary role of information transfer. Neurons are unique among cells in their morphology, with projections that extend hundreds to thousands of microns. Neuron size and asymmetry pose a challenge for …
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An Exploration of Neural Heterogeneity and its Consequences on Network Dynamics and Neuromodulation
… information transmission, and effective neural encoding. Importantly, although neural heterogeneity is often regarded as a static property and modelled as a fixed meta-parameter, this is not the case in the brain. Rather, heterogeneity is, in many instances, a dynamic property of the …
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Testing the limits of human vision with quantum states of light
… in the brain (which have complex effects on neural excitability and visual perception) might impact the detection of few-photon stimuli.
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Noise-induced cochlear neuronal degeneration and its role in hyperacusis -- and tinnitus-like behavior
… alteration specifically of auditory neural pathways. Despite significantly reduced cochlear nerve response, seen as reduced wave 1 of the auditory brainstem response, later peaks were unchanged or enhanced, suggesting neural hyperactivity in the auditory brainstem that could underlie …
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Multifocal Transcranial Direct Current Stimulation to Modulate Motor Learning
… brain stimulation technique that modulates neural excitability in targeted brain regions, influencing processes such as motor learning. While tDCS has been previously shown to benefit motor skill acquisition, much of this research has focused on relatively simple, unimanual tasks. …
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Uncovering Zn2+ and Ca2+ Homeostasis and Crosstalk in Primary Hippocampal Neurons
… and are driven by glutamate-mediated spontaneous neural excitability. Cellular acidification is the bridge that connects Zn<sup>2+</sup> spikes with Ca<sup>2+</sup> spikes. My second project aims to identify the mechanism by which Zn<sup>2+</sup> spikes are generated via Ca<sup>2+</sup> influx. …
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The Effects of Altered Partial Pressures of Gas on Cognitive and Neural Function
Oxygen is central to neural function, yet the precise mechanisms and effects by which varying <br/>oxygen levels, whether through Hypoxia, Hyperoxia, or Hyperbaric Oxygen Therapy (HBOT), <br/>shape cognition and brain activity remain incomplete. This thesis adopts a novel, multi-modal …
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Elucidation of the Role of miR-184 in the Development and Maintenance of the Drosophila Melanogaster Nervous System
… sodium channel, shown to control neuronal excitability; and (ii) tramtrack69 (ttk69), a transcription factor known to regulate glial cell number and fate determination during embryonic development. In the absence of miR-184, homozygous loss-of-function mutant adult flies demonstrate …
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Electromagnetic Field Modeling of Transcranial Electric and Magnetic Stimulation: Targeting, Individualization, and Safety of Convulsive and Subconvulsive Applications
… transmembrane potentials and, thereby, neuronal excitability or activity. Therefore, knowledge of the induced electric field distribution is key in the design and interpretation of basic research and clinical studies. This work aims to delineate the fundamental physical limitations, tradeoffs, …