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Showing 1 to 3 of 3 for “"Net1"”.
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Regulation of Net1A Subcellular Localization By The Small Gtpase Rac1
… GEFs). The neuroepithelioma transforming gene 1 (Net1) is a Rho GEF specific for the RhoA subfamily that is overexpressed in primary breast tumors and breast cancer cell lines. Net1 isoform expression is also required for migration and invasion of breast cancer cells in vitro. These data indicate …
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The Src- and Abl- Dependent Regulation of Net1A In Breast Cancer
<p>The neuroepithelial cell transforming gene 1 (Net1) is a RhoA guanine nucleotide exchange factor that promotes cancer cell motility and metastasis. Two isoforms of Net1 exist, Net1 and Net1A, both of which are which sequestered in the nucleus in quiescent cells to prevent aberrant RhoA …
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The role of RNAs and extracellular vesicles in the radiation response
… a functional study of the genes ANP32B, MALAT1, NET1, HSP90AA1 and NCL was performed based upon their upregulation in 2 Gy EVs. Knockdown of some of these genes resulted in changes in the DNA damage response observed in directly irradiated and bystander cells, suggesting that the RNAs carried in …