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Showing 1 to 2 of 2 for “"Nervous system -- Diseases--Treatment."”.

  1. Polyglutamine monomer structure and its implications for molecular self-assembly

    … has been implicated in several neurodegenerative diseases, including Huntington's disease. The resulting aggregates have been demonstrated to possess ~-sheet structure, and aggregation has been shown to start with a single misfolded peptide. The current project sought to computationally examine …

    brock Repository record for Polyglutamine monomer structure and its implications for molecular self-assembly (opens in a new tab)

  2. The Physical Mechanism of Blood-Brain Barrier Opening Using Focused Ultrasound and Microbubbles

    The key to effective treatment of neurological diseases resides in the safe opening of the blood-brain barrier (BBB), a specialized structure that impedes the delivery of therapeutic agents to the parenchyma. Despite the fact that several approaches have been successful in overcoming the BBB …

    columbia-diss Repository record for The Physical Mechanism of Blood-Brain Barrier Opening Using Focused Ultrasound and Microbubbles (opens in a new tab)