Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Neoplastic Stem Cells"”.
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Cellular Mechanisms of Cancer Stem Cells
The file named "bhagwandinvikash.pdf" is the primary dissertation file. To access the supplemental video, click on the file named "3D_BLI_of_Pancreatic_Tumor.mpg".
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Telomere Length Studies in Human Cancer Cells
… of repair. The telomeres of most normal diploid cells shorten with every cell division until they reach a critically short length, at which time the cells undergo senescence or apoptosis. Cancer cells which have the ability to divide indefinitely must prevent their telomeres from becoming …
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Histone Demethylase LSD1 Restricts the Size of the Germline Stem Cell Niche in Drosophila Ovaries
Specialized microenvironments called niches keep stem cells in an undifferentiated and self-renewing state by producing a variety of factors. The size and signaling output of niches must be finely tuned to ensure proper tissue homeostasis. I use the Drosophila female germline as an excellent model …
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Examining the Regulation and Function of Cancer Testis Antigens
… to the testis, but are reactivated in cancer cells. The function and regulation of many CTAs are unknown, however several CTAs have been shown to impact tumor cell fitness and correlate with poor prognosis. Our lab became interested in CTAs after a pan-genomic-loss-of-function RNAi screen …